瘙痒症：对一个老问题的新审视。
Pruritus: an updated look at an old problem.
作者信息
Tivoli Yvette A, Rubenstein Richard M
机构信息
Palmetto General Hospital, Hialeah, Florida.
出版信息
J Clin Aesthet Dermatol. 2009 Jul;2(7):30-6.
Abstract
Pruritus is among the most common dermatological complaints. The authors examine the pathophysiology of itch according to the most common mediators uncovered by researchers. They also discuss the encompassing etiologies, which include dermatological, psychological, and systemic causes. Finally, they discuss the diagnostic approach and the latest, most appropriate treatment options. (J Clin Aesthetic Dermatol. 2009;2(7):30-36.).
摘要
瘙痒是最常见的皮肤科症状之一。作者根据研究人员发现的最常见介质来研究瘙痒的病理生理学。他们还讨论了包括皮肤病学、心理学和全身性病因在内的各种病因。最后，他们讨论了诊断方法以及最新、最合适的治疗选择。（《临床美容皮肤科杂志》。2009年；2(7):30 - 36。）
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本文引用的文献
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Relief of itch by scratching: state-dependent inhibition of primate spinothalamic tract neurons.搔抓止痒：灵长类动物脊髓丘脑束神经元的状态依赖性抑制
Nat Neurosci. 2009 May;12(5):544-6. doi: 10.1038/nn.2292. Epub 2009 Apr 6.
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Novel agents for intractable itch.用于治疗顽固性瘙痒的新型药物。
Skin Therapy Lett. 2008 Feb;13(1):6-9.
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Clinical pharmacokinetics and pharmacodynamics of desloratadine, fexofenadine and levocetirizine : a comparative review.地氯雷他定、非索非那定和左西替利嗪的临床药代动力学与药效学：一项比较性综述
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Neurophysiological and neurochemical basis of modern pruritus treatment.现代瘙痒治疗的神经生理学和神经化学基础。
Exp Dermatol. 2008 Mar;17(3):161-9. doi: 10.1111/j.1600-0625.2007.00664.x. Epub 2007 Dec 5.
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Treatment of pruritus with topically applied opiate receptor antagonist.局部应用阿片受体拮抗剂治疗瘙痒症。
J Am Acad Dermatol. 2007 Jun;56(6):979-88. doi: 10.1016/j.jaad.2007.01.007. Epub 2007 Feb 22.
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A comparison of levocetirizine and desloratadine in the histamine-induced wheal and flare response in human skin in vivo.左西替利嗪与地氯雷他定在人体皮肤组胺诱导的风团及潮红反应中的体内比较。
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