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心脏和血管周围的脂肪组织在动脉粥样硬化中起作用吗?

Do cardiac and perivascular adipose tissue play a role in atherosclerosis?

作者信息

Iacobellis Gianluca, Gao Yu-Jing, Sharma Arya M

机构信息

Department of Medicine, St. Joseph's Hospital, 50 Charlton Avenue East, 5th Fontbonne Building, Hamilton, Ontario, L8N 4A6, Canada.

出版信息

Curr Diab Rep. 2008 Feb;8(1):20-4. doi: 10.1007/s11892-008-0005-2.

DOI:10.1007/s11892-008-0005-2
PMID:18366994
Abstract

Recent evidence suggests that epicardial and perivascular adipose tissue could mechanically and functionally affect the heart and vasculature, thereby possibly playing a role in adiposity-related atherosclerosis. Experimental and clinical observations suggest both favorable and unfavorable effects of epicardial and perivascular fat. The double role of epicardial and perivascular adipose tissue in the development of cardiovascular pathology and/or in protecting the heart and arteries warrants further studies.

摘要

最近的证据表明,心外膜和血管周围脂肪组织可在机械和功能上影响心脏和血管,从而可能在肥胖相关动脉粥样硬化中发挥作用。实验和临床观察表明心外膜和血管周围脂肪既有有利影响,也有不利影响。心外膜和血管周围脂肪组织在心血管病理发展和/或保护心脏及动脉方面的双重作用值得进一步研究。

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Relation of subepicardial adipose tissue to carotid intima-media thickness in patients with human immunodeficiency virus.人类免疫缺陷病毒患者的心外膜下脂肪组织与颈动脉内膜中层厚度的关系
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Effects of weight loss after bariatric surgery on epicardial fat measured using echocardiography.减肥手术后体重减轻对使用超声心动图测量的心外膜脂肪的影响。
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Echocardiographic epicardial fat thickness and coronary artery disease.
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The Role and Implications of Epicardial Fat in Coronary Atherosclerotic Disease.心外膜脂肪在冠状动脉粥样硬化性疾病中的作用及影响
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Relation of Menopause With Cardiovascular Risk Factors in South Asian American Women (from the MASALA Study).南亚裔美国女性的绝经与心血管危险因素的关系(来自 MASALA 研究)。
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