Kullmann Tamás, Barta Imre, Antus Balázs, Horváth Ildikó
Department of Pathophysiology, National Korányi Institute for TB and Pulmonology, Pihenő u. 1, Budapest, 1529, Hungary.
Institute of Human Physiology and Clinical Experimental Research, Semmelweis University, Budapest, Hungary.
Lung. 2008 Jul-Aug;186(4):263-268. doi: 10.1007/s00408-008-9086-6. Epub 2008 Mar 27.
Exhaled breath condensate analysis is a developing method for investigating airway pathology. Impact of food and drink on breath condensate composition has not been systematically addressed. The aim of the study was to follow exhaled breath condensate pH after drinking an acidic and a neutral beverage. Breath condensate, capillary blood, and urine of 12 healthy volunteers were collected before and after drinking either 1 l of coke or 1 l of mineral water. The pH of each sample was determined with a blood gas analyzer. The mean difference between the pH of two breath condensate samples collected within 15 min before drinking was 0.13+/-0.03. Condensate pH decreased significantly from 6.29+/-0.02 to 6.24+/-0.02 (p<0.03) after drinking coke and from 6.37+/-0.03 to 6.22+/-0.04 (p<0.003) after drinking water. Drinking coke induced significant changes in blood and urine pH as well. Drinking influences exhaled breath condensate composition and may contribute to the variability of exhaled breath condensate pH.
呼出气冷凝液分析是一种用于研究气道病理的新兴方法。食物和饮料对呼出气冷凝液成分的影响尚未得到系统研究。本研究的目的是观察饮用酸性饮料和中性饮料后呼出气冷凝液的pH值变化。12名健康志愿者在饮用1升可乐或1升矿泉水前后，分别采集了呼出气冷凝液、毛细血管血和尿液样本。使用血气分析仪测定每个样本的pH值。饮用前15分钟内采集的两份呼出气冷凝液样本的pH值平均差异为0.13±0.03。饮用可乐后，冷凝液pH值从6.29±0.02显著降至6.24±0.02（p<0.03），饮用矿泉水后从6.37±0.03降至6.22±0.04（p<0.003）。饮用可乐也会引起血液和尿液pH值的显著变化。饮用会影响呼出气冷凝液的成分，并可能导致呼出气冷凝液pH值的变化。
