Kemper Kathi J, Hamilton Craig A, McLean Thomas W, Lovato James
Department of Pediatrics, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, USA.
Pediatr Res. 2008 Jul;64(1):105-9. doi: 10.1203/PDR.0b013e318174e6fb.
Music is widely used to enhance well-being. We wished to assess music's effect on pediatric oncology outpatients. Patients who had leukemia and were in maintenance or consolidation outpatient treatment served as their own control at two visits. At visit 1, children rested for 20 min; at visit 2, for 20 min they listened to music designed to increase vitality and improve heart rate variability (HRV). At both visits, parents completed before and after treatment visual analog scales (VAS) of their child's relaxation, well-being, vitality, anxiety, stress, and depression; patients' heart rates were monitored during treatments to calculate HRV. The 47 patients with complete VAS data and 34 patients with usable HRV data were similar. At baseline, VAS scores for negative states were low (average <2.5 of 10) and positive states were high (average 7> of 10). Relaxation improved more with music than rest (p < 0.01). The HRV parasympathetic parameter was significantly lower with music than rest. No other differences were significant. Further studies are needed to better delineate the relationship between subjective and objective measures of well-being among patients who are not in severe distress.
音乐被广泛用于提升幸福感。我们希望评估音乐对儿科肿瘤门诊患者的影响。患有白血病且处于维持或巩固期门诊治疗的患者在两次就诊时以自身作为对照。在第一次就诊时,儿童休息20分钟;在第二次就诊时,他们听旨在增强活力和改善心率变异性(HRV)的音乐20分钟。在两次就诊时,家长均在治疗前后完成关于孩子放松、幸福感、活力、焦虑、压力和抑郁的视觉模拟量表(VAS);在治疗期间监测患者的心率以计算HRV。47例有完整VAS数据的患者和34例有可用HRV数据的患者情况相似。在基线时,负面状态的VAS评分较低(平均<10分中的2.5分),正面状态的评分较高(平均>10分中的7分)。与休息相比,听音乐时放松程度改善更明显(p<0.01)。听音乐时HRV的副交感神经参数显著低于休息时。其他方面无显著差异。需要进一步研究以更好地描绘未处于严重痛苦状态的患者幸福感主观和客观指标之间的关系。