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特发性正常压力脑积水管理指南。

Guidelines for management of idiopathic normal pressure hydrocephalus.

作者信息

Ishikawa Masatsune, Hashimoto Masaaki, Kuwana Nobumasa, Mori Etsuro, Miyake Hiroji, Wachi Akihiko, Takeuchi Totaro, Kazui Hiroaki, Koyama Hiroshi

机构信息

Kitano Hospital, Japan.

出版信息

Neurol Med Chir (Tokyo). 2008;48 Suppl:S1-23. doi: 10.2176/nmc.48.s1.

Abstract

With the rapid aging of Japanese society, medical care of the elderly has become an important social issue. Among various disorders manifesting dementia, gait disturbance, and urinary incontinence in the elderly population, normal pressure hydrocephalus (NPH), especially of idiopathic type (iNPH), is becoming noteworthy. The Guidelines for management of iNPH in Japan are created in compliance with the evidence-based medicine methods and published in 2004. This English version is made to show the diagnosis and treatment of iNPH with reference to the socio-medical background in Japan and to promote the international research on iNPH. They propose three diagnostic levels; possible, probable, and definite. They indicate the diagnostic importance of high convexity tightness and dilated sylvian fissure with mild to moderate ventriculomegaly on coronal magnetic resonance imaging. The cerebrospinal fluid tap test is regarded as an important diagnostic test because of its simplicity to perform and high predictability of the shunt efficacy. The use of programmable valves at shunt surgeries is recommended. Flowcharts for diagnosis, preoperative assessment, and prevention for complications of shunt surgery are made to promote a wide use of them.

摘要

随着日本社会的快速老龄化,老年人的医疗保健已成为一个重要的社会问题。在老年人群中出现的各种痴呆、步态障碍和尿失禁病症中,正常压力脑积水(NPH),尤其是特发性类型(iNPH),正变得值得关注。日本的iNPH管理指南是按照循证医学方法制定的,并于2004年发布。这个英文版本旨在结合日本的社会医学背景展示iNPH的诊断和治疗,并促进关于iNPH的国际研究。指南提出了三个诊断级别:可能、很可能和确诊。它们指出了在冠状位磁共振成像上高凸度紧绷和轻度至中度脑室扩大伴大脑外侧裂增宽的诊断重要性。脑脊液引流试验因其操作简单且对分流效果的预测性高而被视为一项重要的诊断试验。建议在分流手术中使用可编程阀门。制定了诊断、术前评估和分流手术并发症预防的流程图,以促进其广泛应用。

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