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High-resolution genotyping of Aspergillus fumigatus isolates recovered from chronically colonised patients with cystic fibrosis.

作者信息

Vanhee L M E, Symoens F, Bouchara J-P, Nelis H J, Coenye T

机构信息

Laboratory for Pharmaceutical Microbiology, Ghent University, Ghent, Belgium.

出版信息

Eur J Clin Microbiol Infect Dis. 2008 Oct;27(10):1005-7. doi: 10.1007/s10096-008-0527-1. Epub 2008 May 6.

DOI:10.1007/s10096-008-0527-1
PMID:18458971
Abstract

A series of 256 Aspergillus fumigatus isolates, recovered from eight patients with cystic fibrosis (CF), were genotyped using microsatellite-based typing. Only a limited number of genotypes were shared between patients and co-colonisation with multiple strains was indicated for all patients. Additionally, some genotypes were isolated recurrently, indicating that they are capable of prolonged colonisation.

摘要

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Use of a novel panel of nine short tandem repeats for exact and high-resolution fingerprinting of Aspergillus fumigatus isolates.使用一组由九个短串联重复序列组成的新型组合对烟曲霉分离株进行精确且高分辨率的指纹图谱分析。
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Mycopathologia. 2018 Dec;183(6):913-920. doi: 10.1007/s11046-018-0297-y. Epub 2018 Sep 6.
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