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德黑兰视网膜疾病的患病率及其模式:德黑兰眼科研究

Prevalence of retinal diseases and their pattern in Tehran: the Tehran eye study.

作者信息

Hatef Elham, Fotouhi Akbar, Hashemi Hassan, Mohammad Kazem, Jalali Kamran Hodjat

机构信息

Noor Vision Correction Centre, Tehran, Iran.

出版信息

Retina. 2008 May;28(5):755-62. doi: 10.1097/IAE.0b013e3181613463.

DOI:10.1097/IAE.0b013e3181613463
PMID:18463522
Abstract

PURPOSE

To determine the prevalence of retinal diseases and their pattern in Tehran through a population-based study.

METHODS

In 2002, through a stratified random cluster sampling, 6497 citizens representing a cross-section of the population of Tehran were selected from 160 clusters. Eligible people were recruited through a door-to-door household survey in selected clusters and transferred to a clinic for an extensive eye examination and interview.

RESULTS

The prevalence of retinal diseases was 8.56 per 100 (95% CI, 7.74-9.39). Acquired retinopathies (3.33 per 100) and peripheral retinal lesions (3.29 per 100) were the most common retinal diseases in our population. Cataract (12.47 per 100) was the major ocular comorbidity; high blood pressure (21.14 per 100) and diabetes mellitus (15.99 per 100) were the main systemic comorbidities among 415 patients with retinal diseases. The prevalence of low vision on the basis of best-corrected and presenting visual acuity was 0.63 and 2.87 per 100 in 415 patients with retinal disease. Two patients (0.48 per 100) were blind with corrected and presenting visual acuity. The prevalence of diabetic retinopathy in the studied population was 0.61 per 100 (95% CI, 0.39-0.82) and age-related macular degeneration was detected in 1.95 per 100 (95% CI, 1.55-2.34) of the population.

CONCLUSIONS

These findings reveal a considerable prevalence of retinal diseases in the population. The prevalence might be underestimated due to the lack of fundus photography. The findings could be considered for case finding and planning treatment programs for specific retinal diseases.

摘要

目的

通过一项基于人群的研究,确定德黑兰视网膜疾病的患病率及其模式。

方法

2002年,通过分层随机整群抽样,从160个群组中选取了代表德黑兰人口横断面的6497名市民。符合条件的人员通过在选定群组中进行的挨家挨户的家庭调查招募,并被转移到诊所进行全面的眼部检查和访谈。

结果

视网膜疾病的患病率为每100人中有8.56例(95%可信区间,7.74 - 9.39)。获得性视网膜病变(每100人中有3.33例)和周边视网膜病变(每100人中有3.29例)是我们研究人群中最常见的视网膜疾病。白内障(每100人中有12.47例)是主要的眼部合并症;高血压(每100人中有21.14例)和糖尿病(每100人中有15.99例)是415例视网膜疾病患者中的主要全身合并症。在415例视网膜疾病患者中,根据最佳矫正视力和就诊视力计算的低视力患病率分别为每100人中有0.63例和2.87例。两名患者(每100人中有0.48例)矫正视力和就诊视力均为失明。研究人群中糖尿病视网膜病变的患病率为每100人中有0.61例(95%可信区间,0.39 - 0.82),年龄相关性黄斑变性在每100人中有1.95例(95%可信区间,1.55 - 2.34)被检测到。

结论

这些发现揭示了该人群中视网膜疾病的患病率相当高。由于缺乏眼底摄影,患病率可能被低估。这些发现可用于病例发现和为特定视网膜疾病制定治疗计划。

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