Heitmar Rebekka, Gherghel Doina, Armstrong Richard, Cubbidge Robert, Hosking Sarah
School of Life and Health Sciences, Aston University, Birmingham, UK.
J Med Case Rep. 2008 May 13;2:153. doi: 10.1186/1752-1947-2-153.
Dynamic retinal vessel analysis represents a well-established method for the assessment of vascular reactivity during both normal conditions and after various provocations. We present a case where the subject showed abnormal retinal vessel reactivity after fasting voluntarily for 20 hours.
A healthy, 21-year-old man who fasted voluntarily for 20 hours exhibited abnormal retinal vascular reactivity (dilation and constriction) after flicker provocation as measured using the Dynamic Retinal Vessel Analyser (Imedos, Jena, Germany).
The abnormal vascular reactivity induced by fasting was significant; abnormal levels of important nutrients due to fasting and dehydration could play a role through altering the concentration of vasoactive substances such as nitric oxide. This hypothesis needs further investigation.
动态视网膜血管分析是一种成熟的方法，用于评估正常情况下以及各种刺激后血管的反应性。我们报告一例受试者在自愿禁食20小时后出现异常视网膜血管反应性的病例。
一名健康的21岁男性自愿禁食20小时，在使用动态视网膜血管分析仪（德国耶拿的Imedos公司生产）进行闪烁刺激后，表现出异常的视网膜血管反应性（扩张和收缩）。
禁食引起的异常血管反应性很显著；禁食和脱水导致的重要营养素水平异常可能通过改变一氧化氮等血管活性物质的浓度发挥作用。这一假设需要进一步研究。
