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在基因组学时代进行曲霉属菌株分型。

Aspergillus strain typing in the genomics era.

机构信息

Department of Medical Microbiology and Infectious Diseases, Canisius Wilhelmina Hospital, Nijmegen, The Netherlands.

出版信息

Stud Mycol. 2007;59:47-51. doi: 10.3114/sim.2007.59.06.

Abstract

Multiple reasons may justify a need for strain typing purposes, but the most common reason is to delineate the epidemiological relationships between isolates. The availability of whole genome sequences has greatly influenced our ability to develop highly targeted and efficient strain typing methods fur these purposes. Some strain typing methods may serve dual goals: not only can they be used to discriminate between multiple isolates of a certain species, they can also aid in the recognition, identification, description and validation process of a fungal species.

摘要

有多种原因可能需要对菌株进行分型,但最常见的原因是为了阐明分离株之间的流行病学关系。全基因组序列的出现极大地影响了我们开发针对这些目的的高度靶向和有效的菌株分型方法的能力。一些菌株分型方法可能具有双重目的:它们不仅可用于区分特定物种的多个分离株,还可帮助识别、鉴定、描述和验证真菌物种的过程。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5208/2275195/b3e8487e1878/6fig1.jpg

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