UNICAMP, Rua Dr. Roxo Moreira, 83 Ciadade Universitária, Campina, São Paulo, Brasil CEP: 13083-590.
Int J Cosmet Sci. 1999 Feb;21(1):1-5. doi: 10.1046/j.1467-2494.1999.181658.x.
The aim of this work was to evaluate the correlation between in vitro and in vivo determinations of sun protection factors (SPF) of sunscreen lotions containing the synthetic sunscreen octyl methoxycinnamate. Three sunscreen lotions containing either 2, 4.5 or 7.5% octyl methoxycinnamate were prepared. The in vitro SPFs of these sunscreen lotions were determined according to the spectrophotometric method of Mansur et al. The in vivo SPF values were determined according to the Food and Drug Administration (FDA) method. The results indicate that there was a good correlation between the in vitro and in vivo determinations for the sunscreen lotions examined.
本工作旨在评估含有合成防晒剂辛基甲氧基肉桂酸酯的防晒乳液的体外和体内测定的防晒因子 (SPF) 之间的相关性。制备了三种含有 2%、4.5%或 7.5%辛基甲氧基肉桂酸酯的防晒乳液。根据 Mansur 等人的分光光度法测定这些防晒乳液的体外 SPF 值。根据美国食品和药物管理局 (FDA) 的方法测定体内 SPF 值。结果表明，所检查的防晒乳液的体外和体内测定之间存在良好的相关性。
