Muffly Tyler, McCormick T Chad, Cook Christopher, Wall Jeffrey
Department of Obstetrics and Gynecology, University of Missouri at Kansas City, Kansas City, MO 64108, USA.
Infect Dis Obstet Gynecol. 2008;2008:359172. doi: 10.1155/2008/359172.
The goal of this case is to review the zoonotic infection, human granulocytic ehrlichiosis, presenting with pyrexia. Case. A 22-year-old multigravid female presented to the emergency department with a painful skin rash, high fever, and severe myalgias. The patient underwent a diagnostic evaluation for zoonotic infections due to her geographical and seasonal risk factors. Treatment of human granulocytic ehrlichiosis was successful though the patient spontaneously aborted presumably due to the severity of the acute illness.
Treatment of human granulocytic ehrlichiosis in pregnancy presents unique challenges. Management of pyrexia during pregnancy is limited to external cooling in the setting of thrombocytopenia and elevated aminotransferases. Extensive counseling regarding teratogenic potential of medications allows the patient to weigh the pros and cons of treatment.
本病例的目的是回顾以发热为表现的人畜共患感染——人粒细胞埃立克体病。病例:一名22岁的多孕女性因皮肤皮疹疼痛、高热和严重肌痛就诊于急诊科。由于其地理和季节风险因素,该患者接受了人畜共患感染的诊断评估。尽管患者可能因急性疾病的严重程度而自然流产,但人粒细胞埃立克体病的治疗是成功的。
妊娠期人粒细胞埃立克体病的治疗存在独特挑战。在血小板减少和转氨酶升高的情况下,妊娠期发热的管理仅限于外部降温。关于药物致畸潜力的广泛咨询使患者能够权衡治疗的利弊。