Kingman Albert, Susin Cristiano, Albandar Jasim M
Biostatistics Core, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA.
J Clin Periodontol. 2008 Aug;35(8):659-67. doi: 10.1111/j.1600-051X.2008.01243.x. Epub 2008 May 30.
The study aim was to assess bias magnitudes of periodontal disease severity estimates for specific partial recording protocols (PRPs) in epidemiological studies.
Estimates of mean clinical attachment loss (MCAL) and mean probing pocket depth (MPPD) were derived for 20 different PRPs using full-mouth periodontal data from 1437 dentate Brazilian subjects 14-103 years old having at least four teeth. Biases, relative biases and intra-class correlations for all PRPs were evaluated. Graphical methods were used to assess how well the PRP-based estimates agreed with full-mouth scores across levels of disease.
Slightly higher levels of disease were evidenced on lingual than on buccal sites. Seven multi-site PRPs and the Ramfjörd PRP produced small biases in MPPD (-0.17 to 0.04 mm) and MCAL with relative biases under 8% and 4% in absolute value for MPPD and MCAL, respectively. Biases for full- and random half-mouth-based PRPs were similar. The three-site random half-mouth MB-B-DL and the Ramfjörd PRPs produced the smallest biases, with relative biases <3% in absolute value for MPPD and MCAL.
Bias for MPPD or MCAL estimates varies by site type, number of sites per tooth and number of quadrants included in the PRP.
本研究旨在评估流行病学研究中特定局部记录方案(PRP)对牙周疾病严重程度估计的偏差幅度。
利用来自1437名年龄在14 - 103岁、至少有四颗牙齿的巴西有牙受试者的全口牙周数据,得出20种不同PRP的平均临床附着丧失(MCAL)和平均探诊深度(MPPD)估计值。评估了所有PRP的偏差、相对偏差和组内相关性。采用图形方法评估基于PRP的估计值与不同疾病水平下全口评分的一致性。
舌侧部位的疾病水平略高于颊侧部位。七种多部位PRP和Ramfjörd PRP在MPPD(-0.17至0.04 mm)和MCAL方面产生的偏差较小,MPPD和MCAL的相对偏差绝对值分别低于8%和4%。基于全口和随机半口的PRP偏差相似。三点随机半口MB - B - DL和Ramfjörd PRP产生的偏差最小,MPPD和MCAL的相对偏差绝对值<3%。
MPPD或MCAL估计的偏差因部位类型、每颗牙齿的部位数量以及PRP中包含的象限数量而异。