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甲型(H3N2)流感病毒自然感染。针对表面抗原的抗体的产生、持续存在及作用。

Natural infection with influenza A (H3N2). The development, persistance and effect of antibodies to the surface antigens.

作者信息

Smith A J, Davies J R

出版信息

J Hyg (Lond). 1976 Oct;77(2):271-82. doi: 10.1017/s0022172400024712.

Abstract

A technique for estimating antibodies to the neuraminidase antigens of influenza A is described. The antibody response to the haemagglutinin and neuraminidase antigens of influenza A (H3N2) was studied in a boys' public school over the four-year period 1970--4. During this time there were two outbreaks of influenza A and the effect of antibody on the result of natural challenge was investigated. No boy who had homotypic neuraminidase antibody had clinical influenza.

摘要

本文描述了一种用于估计甲型流感神经氨酸酶抗原抗体的技术。在1970年至1974年的四年期间,对一所男子公立学校中甲型流感(H3N2)血凝素和神经氨酸酶抗原的抗体反应进行了研究。在此期间发生了两次甲型流感疫情,并对抗体对自然感染结果的影响进行了调查。没有同型神经氨酸酶抗体的男孩发生临床流感。

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