Arnold Marcel, Camus-Jacqmin Mathilde, Stapf Christian, Ducros Anne, Viswanathan Anand, Berthet Karine, Bousser Marie Germaine
Stroke. 2008 Aug;39(8):2377-9. doi: 10.1161/STROKEAHA.107.510107. Epub 2008 Jun 5.
Cervicocephalic artery dissection (CAD) after childbirth is rare. The objective of this study was to determine differences between postpartum and nonpostpartum CAD.
We compared consecutive patients with postpartum CAD with a control group of women with nonpostpartum CAD.
Of 245 patients with CAD, 102 women <50 years (6 with postpartum CAD and 96 with nonpostpartum CAD) were identified. Vascular risk factors and presenting characteristics did not differ significantly between postpartum CAD and nonpostpartum CAD women. By contrast, patients with postpartum CAD had more often coexisting conditions such as reversible cerebral vasoconstriction syndrome (2 of 6 versus 2 of 96; P=0.017), reversible posterior leukoencephalopathy syndrome (2 of 6 versus one of 96; P=0.009), and subarachnoid hemorrhage without signs of intracranial extension of CAD (2 of 6 versus zero of 96; P=0.003).
CAD and associated conditions should be looked for in women with unusual headache after childbirth.
产后颈脑动脉夹层（CAD）较为罕见。本研究的目的是确定产后CAD与非产后CAD之间的差异。
我们将连续的产后CAD患者与非产后CAD女性对照组进行了比较。
在245例CAD患者中，确定了102名年龄<50岁的女性（6例产后CAD和96例非产后CAD）。产后CAD女性与非产后CAD女性之间的血管危险因素和临床表现无显著差异。相比之下，产后CAD患者更常伴有可逆性脑血管收缩综合征（6例中的2例与96例中的2例；P=0.017）、可逆性后部白质脑病综合征（6例中的2例与96例中的1例；P=0.009）以及无CAD颅内扩展迹象的蛛网膜下腔出血（6例中的2例与96例中的0例；P=0.003）等并存疾病。
产后出现异常头痛的女性应排查CAD及相关疾病。
