Luebbers Paul E, Potteiger Jeffrey A, Warren Beverly J, Clore John N, Jennings Chris, Bond Dale S
Department of Health, Physical Education, and Recreation, Emporia State University, Emporia, Kansas, USA.
J Strength Cond Res. 2008 Jul;22(4):1094-100. doi: 10.1519/JSC.0b013e31816d456f.
High-intensity (HI) resistance exercise augments postexercise glucose uptake to a greater degree than low-intensity (LO) resistance exercise; however, few studies have equated the work volumes between intensity levels. The purpose of this study was to compare the effect of acute HI and LO resistance exercise of equal work volume on glucose uptake in resistant-trained men. Fifteen healthy male (22.9 +/- 3.8 years old), resistance-trained (6.7 +/- 3.9 years) subjects completed three treatment sessions: CON (no-exercise control), HI (3 x 8, 85% 10-RM), and LO (3 x 15, 45% 10-RM). HI and LO sessions consisted of eight exercises. Glucose uptake was measured the following morning by using the hyperinsulinemic euglycemic clamp technique. Glucose disposal was measured by analyzing the glucose infusion rate during the final 30 minutes of steady-state blood glucose concentrations. Insulin sensitivity was calculated by dividing the glucose infusion rate by the average insulin infusion. Results indicate that fasting blood glucose levels were not significantly different among treatment sessions (CON = 80.5 +/- 5.3 versus HI = 77.0 +/- 4.9 versus LO = 77.1 +/- 6.0 mg.dL). Glucose uptake was not significantly different among treatment sessions (CON = 11.3 +/- 3.0 versus HI = 11.7 +/- 2.7 versus LO = 11.4 +/- 2.8 mg.kg FFM.min). Insulin sensitivity did not change among treatment sessions (CON = 0.26 +/- 0.09 versus HI = 0.28 +/- 0.07 versus LO = 0.27 +/- 0.06 (mg.kg FFM.min)/(uU.mL)). The data indicate that the resistance training sessions did not modify acute insulin sensitivity. This may have been because of the high levels of fitness of the subjects, which allowed for the cellular adaptations for enhanced insulin sensitivity and glucose uptake that are unaffected by this volume of acute exercise.
高强度（HI）抗阻运动比低强度（LO）抗阻运动能更大程度地增强运动后葡萄糖摄取；然而，很少有研究使不同强度水平之间的运动量相等。本研究的目的是比较相同运动量的急性HI和LO抗阻运动对有抗阻训练男性葡萄糖摄取的影响。15名健康男性（22.9±3.8岁），有抗阻训练经历（6.7±3.9年），完成了三个治疗阶段：CON（无运动对照）、HI（3组，每组8次，85%的10次重复最大负荷）和LO（3组，每组15次，45%的10次重复最大负荷）。HI和LO阶段包括八项运动。次日早晨使用高胰岛素正常血糖钳夹技术测量葡萄糖摄取。通过分析稳态血糖浓度最后30分钟期间的葡萄糖输注速率来测量葡萄糖处置。通过将葡萄糖输注速率除以平均胰岛素输注量来计算胰岛素敏感性。结果表明，各治疗阶段的空腹血糖水平无显著差异（CON = 80.5±5.3，HI = 77.0±4.9，LO = 77.1±6.0mg/dL）。各治疗阶段的葡萄糖摄取无显著差异（CON = 11.3±3.0，HI = 11.7±2.7，LO = 11.4±2.8mg/kg去脂体重·分钟）。各治疗阶段的胰岛素敏感性无变化（CON = 0.26±0.09，HI = 0.28±0.07，LO = 0.27±0.06（mg/kg去脂体重·分钟）/（uU/mL））。数据表明抗阻训练阶段并未改变急性胰岛素敏感性。这可能是因为受试者的健康水平较高，这使得细胞适应增强胰岛素敏感性和葡萄糖摄取，而不受该运动量急性运动的影响。
