Department of Physical Medicine and Rehabilitation, Laboratory for Physical Activity and Exercise Intervention Research, University of Michigan, Ann Arbor, MI, USA.
Eur J Appl Physiol. 2011 Jun;111(6):1063-71. doi: 10.1007/s00421-010-1735-9. Epub 2010 Nov 27.
Volume load (VL) is suggested to influence the adaptation of muscle to resistance exercise (RE). We sought to examine the independent association between total VL and hypertrophy and strength following a progressive RE protocol of equated sets and intensity. Total VL was calculated in 83 subjects (n = 43 males, n = 40 females; age = 25.12 ± 5.5 years) who participated in unilateral arm RE for 12 weeks. Subjects were tested for biceps muscle volume (MRI of the upper arm), isometric maximal voluntary contraction (MVC), and dynamic biceps strength (1RM), at baseline and following RE. Linear regression analysis revealed that sex was a significant predictor of hypertrophy (β = 0.06; p = 0.01) and strength (β = 0.14; p = 0.04), and that males had greater increases. Total VL was independently associated with hypertrophy only among females (β = 0.12; p < 0.01). For males, only baseline strength was (inversely) related to hypertrophy (β = -0.12; p = 0.04). VL was strongly associated with changes in 1RM strength improvement for both males (β = 0.66; p < 0.01) and females (β = 0.26; p = 0.02), but only related to MVC among females (β = 0.20; p = 0.02). Findings reveal that VL was independently associated with hypertrophy only among females. For males baseline strength was independently and inversely related to changes in muscle mass. Conversely, VL was found to be strongly associated with changes in 1RM for both males and females, controlling for age, body mass, and baseline strength.
容积负荷（VL）被认为会影响肌肉对抵抗运动（RE）的适应。我们旨在研究在等集和强度递增的 RE 方案后，总 VL 与肥大和力量之间的独立关联。83 名受试者（男性 43 名，女性 40 名；年龄 25.12±5.5 岁）参与了单侧手臂 RE12 周，计算了他们的总 VL。在 RE 前后，对受试者的二头肌肌肉体积（上臂 MRI）、等长最大自主收缩（MVC）和二头肌动态强度（1RM）进行了测试。线性回归分析显示，性别是肥大（β=0.06；p=0.01）和力量（β=0.14；p=0.04）的显著预测因素，男性的增加幅度更大。总 VL 仅与女性的肥大独立相关（β=0.12；p<0.01）。对于男性，仅基线力量与肥大呈负相关（β=-0.12；p=0.04）。VL 与男性（β=0.66；p<0.01）和女性（β=0.26；p=0.02）1RM 强度改善的变化均密切相关，但仅与女性的 MVC 相关（β=0.20；p=0.02）。研究结果表明，VL 仅与女性的肥大独立相关。对于男性，基线力量与肌肉质量的变化独立且呈负相关。相反，VL 与男性和女性的 1RM 变化密切相关，控制了年龄、体重和基线强度。
