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临床医学中的白细胞介素-6

Interleukin-6 in clinical medicine.

作者信息

Bauer J, Herrmann F

机构信息

Psychiatrische Universitätsklinik, Universität Freiburg, FRG.

出版信息

Ann Hematol. 1991 Jun;62(6):203-10. doi: 10.1007/BF01729833.

DOI:10.1007/BF01729833
PMID:1854882
Abstract

This article covers the basic biological functions of interleukin-6 (IL-6) in man. Three major topics are addressed more closely: the involvement of IL-6 in various disease states, particularly those of hematopoietic origin; the diagnostic usefulness of IL-6 measurements in biological fluids; the possible use of IL-6, IL-6 antagonists or IL-6 derivatives as therapeutic means.

摘要

本文涵盖了白细胞介素-6（IL-6）在人体中的基本生物学功能。更深入地探讨了三个主要主题：IL-6在各种疾病状态中的作用，尤其是造血系统起源的疾病；IL-6在生物体液检测中的诊断价值；IL-6、IL-6拮抗剂或IL-6衍生物作为治疗手段的潜在用途。

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Ann Hematol. 1991 Jun;62(6):203-10. doi: 10.1007/BF01729833.
2
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Isolation and characterization of B cell differentiation factor (BCDF) secreted from a human B lymphoblastoid cell line.从人B淋巴母细胞系分泌的B细胞分化因子（BCDF）的分离与鉴定
J Immunol. 1984 Jun;132(6):2948-54.
2
Interleukin 6 enhancement of interleukin 3-dependent proliferation of multipotential hemopoietic progenitors.白细胞介素6增强多能造血祖细胞依赖白细胞介素3的增殖。
Proc Natl Acad Sci U S A. 1987 Dec;84(24):9035-9. doi: 10.1073/pnas.84.24.9035.
3
Structure and expression of human B cell stimulatory factor-2 (BSF-2/IL-6) gene.
脑钠肽、S100b和白细胞介素-6能否预测埃及幕上脑出血患者的神经学后果？
Surg Neurol Int. 2020 Dec 22;11:460. doi: 10.25259/SNI_784_2020. eCollection 2020.
4
Recent Advances in Electrochemical and Optical Biosensors Designed for Detection of Interleukin 6.电化学和光学生物传感器在白细胞介素 6 检测方面的最新进展。
Sensors (Basel). 2020 Jan 23;20(3):646. doi: 10.3390/s20030646.
5
Cytokines as biomarkers of inflammatory response after open versus endovascular repair of abdominal aortic aneurysms: a systematic review.细胞因子作为腹主动脉瘤开放修复与血管内修复后炎症反应的生物标志物：系统评价。
Acta Pharmacol Sin. 2018 Jul;39(7):1164-1175. doi: 10.1038/aps.2017.212. Epub 2018 May 17.
6
Clinical Relevance of Transforming Growth Factor-β1, Interleukin-6 and Haptoglobin for Prediction of Obesity Complications in Prepubertal Egyptian Children.转化生长因子-β1、白细胞介素-6和触珠蛋白对预测青春期前埃及儿童肥胖并发症的临床意义
Open Access Maced J Med Sci. 2015 Mar 15;3(1):105-10. doi: 10.3889/oamjms.2015.017. Epub 2015 Jan 22.
7
Maintenance of the nutritional prognostic index predicts survival in patients with unresectable metastatic colorectal cancer.维持营养预后指数可预测不可切除转移性结直肠癌患者的生存期。
J Cancer Res Clin Oncol. 2015 Feb;141(2):307-13. doi: 10.1007/s00432-014-1799-8. Epub 2014 Aug 15.
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Effects of environmentally-relevant levels of perfluorooctane sulfonate on clinical parameters and immunological functions in B6C3F1 mice.环境相关浓度的全氟辛烷磺酸对 B6C3F1 小鼠临床参数和免疫功能的影响。
J Immunotoxicol. 2011 Jan-Mar;8(1):17-29. doi: 10.3109/1547691X.2010.527868. Epub 2011 Jan 24.
9
Potential role of interleukin 6 in reactive thrombocytosis and acute phase response in pulmonary tuberculosis.白细胞介素6在肺结核反应性血小板增多症及急性期反应中的潜在作用
Postgrad Med J. 2005 Sep;81(959):604-7. doi: 10.1136/pgmj.2004.030544.
10
Cytokine production by CAPAN-1 and CAPAN-2 cell lines.CAPAN-1和CAPAN-2细胞系的细胞因子产生情况。
Dig Dis Sci. 2000 May;45(5):927-32. doi: 10.1023/a:1005573024448.
人B细胞刺激因子-2（BSF-2/IL-6）基因的结构与表达
EMBO J. 1987 Oct;6(10):2939-45. doi: 10.1002/j.1460-2075.1987.tb02598.x.
4
Production of hybridoma growth factor by human monocytes.人单核细胞产生杂交瘤生长因子。
Eur J Immunol. 1987 Oct;17(10):1411-6. doi: 10.1002/eji.1830171004.
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B-cell-stimulatory factor 2 (beta 2 interferon) functions as a second signal for interleukin 2 production by mature murine T cells.B细胞刺激因子2（β2干扰素）作为成熟小鼠T细胞产生白细胞介素2的第二信号发挥作用。
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Human B-cell differentiation factor defined by an anti-peptide antibody and its possible role in autoantibody production.由抗肽抗体定义的人B细胞分化因子及其在自身抗体产生中的可能作用。
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Clin Exp Immunol. 1988 Feb;71(2):320-3.
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Clin Exp Immunol. 1988 Feb;71(2):314-9.
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