Silva Cristiane de Bona da, Guterres Sílvia S, Weisheimer Vanessa, Schapoval Elfrides E S
Pos-Graduation program in Pharmaceuthical Sciences, Pharmaceutical School, Federal University of Rio Grande do Sul, Porto Alegre, RS, Brazil.
Braz J Infect Dis. 2008 Feb;12(1):63-6. doi: 10.1590/s1413-86702008000100014.
Superficial mycoses of the skin are among the most common dermatological infections, and causative organisms include dermatophytic, yeasts, and non-dermatophytic filamentous fungi. The treatment is limited, for many reasons, and new drugs are necessary. Numerous essential oils have been tested for both in vitro and in vivo antifungal activity and some pose much potential as antifungal agents. By using disk diffusion assay, we evaluated the antifungal activity of lemongrass oil and citral against yeasts of Candida species (Candida albicans, C. glabrata, C. krusei, C. parapsilosis and C. tropicalis). This study showed that lemongrass oil and citral have a potent in vitro activity against Candida spp.
皮肤浅表真菌病是最常见的皮肤科感染之一,其致病生物包括皮肤癣菌、酵母菌和非皮肤癣菌丝状真菌。由于多种原因,治疗方法有限,因此需要新药。许多精油已在体外和体内进行抗真菌活性测试,其中一些作为抗真菌剂具有很大潜力。通过纸片扩散法,我们评估了柠檬草油和柠檬醛对念珠菌属酵母菌(白色念珠菌、光滑念珠菌、克柔念珠菌、近平滑念珠菌和热带念珠菌)的抗真菌活性。本研究表明,柠檬草油和柠檬醛对念珠菌属具有强大的体外活性。