Relaxin increases elastase activity and protease inhibitors in smooth muscle cells from the myometrium compared with cells from leiomyomas.
作者信息
Chen Bertha, Wen Yan, Yu Xiao Yun, Polan Mary Lake
机构信息
Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, California, USA.
出版信息
Fertil Steril. 2009 Apr;91(4 Suppl):1351-4. doi: 10.1016/j.fertnstert.2008.03.043. Epub 2008 Jun 12.
Abstract
We investigated the effect of relaxin on extracellular matrix remodeling in cultured myometrial compared with leiomyoma smooth muscle cells. Relaxin increases elastase activity and protease inhibitor expressions in myometrial smooth muscle cells, but no effect was observed in leiomyoma cells.
摘要
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