Krouse Helene J, Yarandi Hossein, McIntosh Jenna, Cowen Celena, Selim Vanessa
College of Nursing, Wayne State University, Detroit, Michigan, USA.
J Asthma. 2008 Jun;45(5):389-95. doi: 10.1080/02770900801971800.
This study evaluated the sleep/wake cycle of individuals with asthma in relation to asthma control, daytime sleepiness, and daytime activity. Ten persons with mild to moderate persistent asthma monitored their sleep quality and daytime wakefulness for 7 consecutive days using 24-hours wrist actigraphy. Degree of asthma control strongly correlated with sleep quality. Individuals whose asthma was not well controlled took longer to fall asleep, awoke more often, and spent more time awake during the night compared to those with well controlled asthma. Poor asthma control, use of rescue medications, and asthma symptoms were associated with daytime sleepiness and limitations in physical activity and emotional function. Forty percent of subjects reported clinically significant daytime sleepiness. Evaluating asthma throughout a 24-hour cycle provides valuable information on variations in the sleep/wake cycle associated with asthma control, use of rescue medications, and asthma symptoms.
本研究评估了哮喘患者的睡眠/觉醒周期与哮喘控制、日间嗜睡及日间活动的关系。10名轻度至中度持续性哮喘患者连续7天使用24小时腕部活动记录仪监测其睡眠质量和日间觉醒情况。哮喘控制程度与睡眠质量密切相关。与哮喘控制良好的患者相比，哮喘控制不佳的患者入睡时间更长、夜间醒来更频繁且夜间清醒时间更长。哮喘控制不佳、使用急救药物及哮喘症状与日间嗜睡、身体活动受限及情绪功能受限有关。40%的受试者报告有临床上显著的日间嗜睡。在24小时周期内评估哮喘可提供有关与哮喘控制、急救药物使用及哮喘症状相关的睡眠/觉醒周期变化的有价值信息。
