Ward R L, Ashley C S, Moseley R H
Appl Environ Microbiol. 1976 Sep;32(3):339-46. doi: 10.1128/aem.32.3.339-346.1976.
The effect of raw and anaerobically digested sludge on heat inactivation of poliovirus was investigated. Raw sludge was found to be very protective of poliovirus plaque-forming ability at all temperatures studied, but digested sludge had variable effects that were highly dependent upon the experimental conditions. In low concentrations and at relatively low inactivation temperatures, digested sludge is nearly as protective of poliovirus as raw sludge. However, at higher tempeatures and concentrations, digested sludge caused a significant acceleration of poliovirus inactivation. The difference between the protective capability of raw and digested sludge is not due to loss of protective material, because this component is present in the solids of digested sludge as well as in those of raw sludge. Instead, the difference is due to a virucidal agent acquired during digestion. Addition of this agent to the solids of either raw or digested sludge reverses the protective potential of these solids during heat treatment of poliovirus.
研究了生污泥和厌氧消化污泥对脊髓灰质炎病毒热灭活的影响。研究发现,在所研究的所有温度下,生污泥对脊髓灰质炎病毒蚀斑形成能力具有很强的保护作用,但消化污泥的作用则有所不同,这高度依赖于实验条件。在低浓度和相对较低的灭活温度下,消化污泥对脊髓灰质炎病毒的保护作用几乎与生污泥相同。然而,在较高温度和浓度下,消化污泥会导致脊髓灰质炎病毒灭活显著加速。生污泥和消化污泥保护能力的差异并非由于保护物质的损失,因为这种成分既存在于消化污泥的固体中,也存在于生污泥的固体中。相反,差异是由于消化过程中获得的一种杀病毒剂。将这种药剂添加到生污泥或消化污泥的固体中,会在脊髓灰质炎病毒热处理过程中逆转这些固体的保护潜力。