在污水污泥中发现一种能降低使呼肠孤病毒失活所需热量的物质。
Discovery of an agent in wastewater sludge that reduces the heat required to inactivate reovirus.
作者信息
Ward R L, Ashley C S
出版信息
Appl Environ Microbiol. 1977 Dec;34(6):681-8. doi: 10.1128/aem.34.6.681-688.1977.
An agent that causes heat inactivation of reovirus to occur at reduced temperatures has been found in both raw and anaerobically digested sludge. This agent is originally associated with sludge solids but can be washed from these solids by blending with water. The activity of the agent was considerably greater in alkaline than in acid solutions, probably because it is insoluble at low pH. The agent was shown to be nonvolatile and heat stable up to 300 degrees C but was inactivated within 30 min at 400 degrees C. The rate of heat inactivation of reovirus by the agent was found to occur in a bimodal fashion and to be relatively rapid, even at 35 degrees C. Finally, it was found that this agent did not accelerate heat inactivation of poliovirus, but instead may be the component of sludge previously found to protect poliovirus against inactivation by heat.
在生污泥和厌氧消化污泥中均发现了一种能使呼肠孤病毒在较低温度下发生热失活的物质。这种物质最初与污泥固体物质相关联，但通过与水混合可从这些固体物质中被洗出。该物质在碱性溶液中的活性比在酸性溶液中高得多，这可能是因为它在低pH值下不溶。研究表明，该物质不挥发，在高达300摄氏度时热稳定，但在400摄氏度下30分钟内会失活。发现该物质使呼肠孤病毒热失活的速率呈双峰模式，并且即使在35摄氏度时也相对较快。最后，发现这种物质不会加速脊髓灰质炎病毒的热失活，反而可能是先前在污泥中发现的能保护脊髓灰质炎病毒免受热失活的成分。
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