拉丁裔女性所生婴儿巨大儿的危险因素。
Risk factors for macrosomia in infants born to Latina women.
作者信息
Wojcicki J M, Hessol N A, Heyman M B, Fuentes-Afflick E
机构信息
Department of Pediatrics, University of California, San Francisco, CA 94110, USA.
出版信息
J Perinatol. 2008 Nov;28(11):743-9. doi: 10.1038/jp.2008.94. Epub 2008 Jul 3.
OBJECTIVE
To assess risk factors for macrosomic infant birth among Latina women.
STUDY DESIGN
Prospective study of Latina women recruited during pregnancy from prenatal clinic at San Francisco General Hospital. Information was obtained through a structured interview and review of medical records.
RESULT
A total of 11% of women delivered macrosomic infants (birth weight >4000 g). In unadjusted analyses, significant risk factors for macrosomia included older maternal age, increasing gravidity, previous history of macrosomic birth and pre-pregnancy overweight. After adjusting for confounders using multivariate analyses, older mothers (10-year increments) had an elevated risk of macrosomia (odds ratio (OR) 2.59; 95% confidence interval (CI) 1.28 to 5.24).
CONCLUSION
Efforts to reduce macrosomia in Latina women should focus on older mothers.
目的
评估拉丁裔女性分娩巨大儿的风险因素。
研究设计
对从旧金山综合医院产前诊所招募的孕期拉丁裔女性进行前瞻性研究。通过结构化访谈和病历审查获取信息。
结果
共有11%的女性分娩出巨大儿（出生体重>4000克）。在未调整分析中，巨大儿的显著风险因素包括产妇年龄较大、妊娠次数增加、既往巨大儿分娩史和孕前超重。在使用多变量分析调整混杂因素后，年龄较大的母亲（每增加10岁）患巨大儿的风险升高（优势比（OR）2.59；95%置信区间（CI）1.28至5.24）。
结论
降低拉丁裔女性巨大儿发生率的努力应聚焦于年龄较大的母亲。
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