University of Tulsa, Tulsa, OK, USA.
J Clin Exp Neuropsychol. 2008 Nov;30(8):920-30. doi: 10.1080/13803390801888733.
Although cognitive deficits are common in persons with multiple sclerosis (MS), the relationship between subjective complaints and objective impairment is sometimes obscured. To elaborate this issue, the present study examined the relationship between subjective complaints of dysexecutive syndrome, neuropsychological performance, and self-reported activities of daily living in 42 people with MS and 13 control participants. Regression analyses revealed that subjective complaints of impairment, measured by the Frontal Systems Behavior Scale (FrSBe), emerged as a significant predictor of neuropsychological deficit and poor adaptive function. Accordingly, subjective complaints of dysexecutive function in MS may serve as a potent indicator of cognitive and functional impairment. Implications for research and clinical practice are discussed.
尽管认知缺陷在多发性硬化症（MS）患者中很常见，但主观抱怨与客观损伤之间的关系有时并不明显。为了详细说明这个问题，本研究调查了 42 名 MS 患者和 13 名对照组参与者的主观执行障碍抱怨、神经心理学表现和自我报告的日常生活活动之间的关系。回归分析显示，用额叶系统行为量表（FrSBe）测量的主观损伤抱怨是神经心理学缺陷和适应功能不良的重要预测指标。因此，MS 患者的执行功能主观抱怨可能是认知和功能损伤的一个有力指标。讨论了对研究和临床实践的意义。
