Harmancey Romain, Taegtmeyer Heinrich
Department of Internal Medicine, Division of Cardiology, University of Texas Medical School at Houston, 6431 Fannin Street, MSB 1.246, Houston, TX 77030, USA.
Curr Diab Rep. 2008 Jun;8(3):243-8. doi: 10.1007/s11892-008-0042-x.
Cardiovascular diseases are foreseeable complications of diabetes mellitus; heart failure is a prominent complication among these. Diabetic cardiomyopathy is a distinct entity independent of coronary artery disease and hypertension. Most of our knowledge on diabetic cardiomyopathy's pathogenesis comes from studies performed on various animal models. The recent advances in the domain confirm that the disease is above all a maladaptation of the heart mostly driven by the metabolic derangements that accompany diabetes mellitus.
心血管疾病是糖尿病可预见的并发症；心力衰竭是其中突出的并发症。糖尿病性心肌病是一种独立于冠状动脉疾病和高血压的独特病症。我们对糖尿病性心肌病发病机制的大部分了解来自于对各种动物模型进行的研究。该领域的最新进展证实，这种疾病首先是心脏的一种适应不良，主要由糖尿病伴随的代谢紊乱所驱动。
