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成人期成熟型小脑畸胎瘤。

Mature cerebellar teratoma in adulthood.

作者信息

Beschorner Rudi, Schittenhelm Jens, Bueltmann Eva, Ritz Rainer, Meyermann Richard, Mittelbronn Michel

机构信息

Institute for Brain Research, University Hospital of Tuebingen, Tuebingen, Germany.

出版信息

Neuropathology. 2009 Apr;29(2):176-80. doi: 10.1111/j.1440-1789.2008.00940.x. Epub 2008 Jul 9.

Abstract

Extragonadal teratomas in adulthood are exceptionally rare and usually not located within the cerebellum. We here report on a 66-year-old male patient clinically presenting with chronic occipital headache and episodes of severe vertigo. Neuroradiological investigations revealed a hemorrhagic tumor mass in the cerebellar vermis which was surgically removed and histologically diagnosed as mature teratoma. Hence, the presented case is extraordinary with regard to age, late clinical onset of symptoms and cerebellar location. Late clinical manifestation of the tumor in this case is probably due to an acute late-onset hemorrhage within the tumor.

摘要

成人性腺外畸胎瘤极为罕见,通常不在小脑内。我们在此报告一名66岁男性患者,临床症状为慢性枕部头痛和严重眩晕发作。神经放射学检查发现小脑蚓部有一个出血性肿瘤肿块,经手术切除并经组织学诊断为成熟畸胎瘤。因此,该病例在年龄、症状出现较晚以及位于小脑等方面都很特殊。该肿瘤在本病例中的晚期临床表现可能是由于肿瘤内急性迟发性出血所致。

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