Anwar Hanny A, Ahmed Qamar A, Bradpiece Howard A
Department of General and Laparoscopic Surgery, Princess Alexandra Hospital, Harlow, UK.
Ann R Coll Surg Engl. 2008 Jul;90(5):394-7. doi: 10.1308/003588408X301037.
Early operations for symptomatic gallstones are gaining favour as the complication rate is thought to be lower and it reduces the overall morbidity. This study was performed to clarify how frequently early operations were being performed and what benefits resulted.
Case notes of 171 patients who underwent laparoscopic cholecystectomy at Princess Alexandra Hospital Harlow were retrospectively reviewed. They were grouped according to their initial diagnosis (cholelithiasis, acute cholecystitis) and the delay to surgery (early, interval). Forty-one cases were excluded as they either had incomplete notes or the initial diagnosis was a different manifestation of gallstones such as pancreatitis. Those receiving interval operations were then grouped according to the mode of their initial presentation. A total of 130 case notes were analysed.
The delay for an interval operation was 3-6 months compared with less than 2 weeks for early operations. Of patients with acute cholecystitis, 43% had early operations but only 12% of patients with cholelithiasis. Waiting for interval operations was associated with multiple re-admissions equivalent to an average of one extra presentation to accident and emergency per patient. This was particularly marked if the initial presentation was to accident and emergency rather than outpatients (P = 0.003). Complication rates were also higher in the interval group.
Early cholecystectomy on the next available list is likely to reduce morbidity and the long-term in-patient burden so should be recommended for all patients presenting as an emergency with symptomatic gallstones.
对于有症状的胆结石患者,早期手术越来越受到青睐,因为人们认为其并发症发生率较低,且能降低总体发病率。本研究旨在明确早期手术的实施频率以及能带来哪些益处。
对哈洛亚历山德拉公主医院171例行腹腔镜胆囊切除术患者的病历进行回顾性分析。根据其初始诊断(胆石症、急性胆囊炎)以及手术延迟情况(早期、间隔期)进行分组。41例患者因病历不完整或初始诊断为胆结石的其他表现(如胰腺炎)而被排除。接受间隔期手术的患者随后根据其初始就诊方式进行分组。共分析了130份病历。
间隔期手术的延迟时间为3至6个月,而早期手术的延迟时间不到2周。急性胆囊炎患者中,43%接受了早期手术,而胆石症患者中只有12%。等待间隔期手术与多次再次入院相关,平均每位患者多一次急诊就诊。如果初始就诊是急诊而非门诊,这种情况尤为明显(P = 0.003)。间隔期手术组的并发症发生率也更高。
在下次有空余手术安排时尽早进行胆囊切除术可能会降低发病率和长期住院负担,因此对于所有因有症状胆结石而急诊就诊的患者都应推荐早期手术。