MetaRoute：快速搜索相关代谢途径以进行交互式网络导航和可视化。
MetaRoute: fast search for relevant metabolic routes for interactive network navigation and visualization.
作者信息
Blum Torsten, Kohlbacher Oliver
机构信息
Division for Simulation of Biological Systems, ZBIT/WSI, University of Tübingen, Tübingen, Germany.
出版信息
Bioinformatics. 2008 Sep 15;24(18):2108-9. doi: 10.1093/bioinformatics/btn360. Epub 2008 Jul 16.
UNLABELLED
We present MetaRoute, an efficient search algorithm based on atom mapping rules and path weighting schemes that returns relevant or textbook-like routes between a source and a product metabolite within seconds for genome-scale networks. Its speed allows the algorithm to be used interactively through a web interface to visualize relevant routes and local networks for one or multiple organisms based on data from KEGG.
AVAILABILITY
http://www-bs.informatik.uni-tuebingen.de/Services/MetaRoute.
SUPPLEMENTARY INFORMATION
Supplementary details are available at http://www-bs.informatik.uni-tuebingen.de/Services/MetaRoute.
未标注
我们展示了MetaRoute，这是一种基于原子映射规则和路径加权方案的高效搜索算法，它能在几秒钟内为基因组规模的网络返回源代谢物和产物代谢物之间的相关或类似教科书的途径。其速度使得该算法能够通过网络界面进行交互式使用，以基于KEGG数据可视化一个或多个生物体的相关途径和局部网络。
可用性
http://www-bs.informatik.uni-tuebingen.de/Services/MetaRoute。
补充信息
补充细节可在http://www-bs.informatik.uni-tuebingen.de/Services/MetaRoute获取。
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