Maddalozzo G F, Iwaniec U T, Turner R T, Rosen C J, Widrick J J
Bone Research Laboratory, Department of Nutrition and Exercise Sciences, Oregon State University, Corvallis, OR 97331, USA.
Int J Obes (Lond). 2008 Sep;32(9):1348-54. doi: 10.1038/ijo.2008.111. Epub 2008 Jul 29.
To evaluate the effects of whole-body vibration on fat, bone, leptin and muscle mass.
METHODS/DESIGN: Thirty 7-month-old female 344 Fischer rats were randomized by weight into three groups (baseline, vibration or control; n=8-10 per group). Rats in the vibration group were placed inside individual compartments attached to a Pneu-Vibe vibration platform (Pneumex, Sandpoint, ID, USA) and vibrated at 30-50 Hz (6 mm peak to peak) for 30 min per day, 5 days per week, for 12 weeks. The vibration intervention consisted of six 5-min cycles with a 1-min break between cycles.
There were significant body composition differences between the whole-body vibration and the control group. The whole-body vibration group weighed approximately 10% less (mean+/-s.d.; 207+/-10 vs 222+/-15 g, P<0.03) and had less body fat (20.8+/-3.8 vs 26.8+/-5.9 g, P<0.05), a lower percentage of body fat (10.2+/-1.7 vs 12+/-2.0%, P<0.05), and lower serum leptin levels (1.06+/-0.45 vs 2.27+/-0.57 ng ml(-1), P<0.01) than the age-matched controls. No differences were observed for total lean mass, bone mineral content (BMC), bone mineral density (BMD), insulin-like growth factor-I (IGF-I) or soleus (SOL) and extensor digitorum longus (EDL) mass or function. Regional high-resolution dual-energy X-ray absoptiometry scans of the lumbar spine (L1-4) revealed that the whole-body vibration group had significantly greater BMC (0.33+/-0.05 vs 0.26+/-0.03 g, P<0.01) and BMD (0.21+/-0.01 vs 0.19+/-0.01 g cm(-2), P<0.01) than the control group. No differences between the groups were observed in the amount of food consumed.
These findings show that whole-body vibration reduced body fat accumulation and serum leptin without affecting whole body BMC, BMD or lean mass. However, the increase in vertebral BMC and BMD suggests that vibration may have resulted in local increases in bone mass and density. Also, whole-body vibration did not affect muscle function or food consumption.
评估全身振动对脂肪、骨骼、瘦素和肌肉质量的影响。
方法/设计：30只7月龄雌性344 Fischer大鼠按体重随机分为三组（基线组、振动组或对照组；每组n = 8 - 10只）。振动组大鼠被放置在连接到Pneu - Vibe振动平台（美国爱达荷州桑德波因特市的Pneumex公司）的单独隔室内，以30 - 50赫兹（峰峰值6毫米）振动，每天30分钟，每周5天，持续12周。振动干预由六个5分钟周期组成，周期之间有1分钟休息时间。
全身振动组与对照组在身体成分上存在显著差异。全身振动组体重减轻约10%（平均值±标准差；207±10克对222±15克，P < 0.03），体脂减少（20.8±3.8克对26.8±5.9克，P < 0.05），体脂百分比降低（10.2±1.7%对12±2.0%，P < 0.05），血清瘦素水平低于年龄匹配的对照组（1.06±0.45纳克/毫升对2.27±0.57纳克/毫升，P < 0.01）。在总瘦体重、骨矿物质含量（BMC）、骨矿物质密度（BMD）、胰岛素样生长因子 - I（IGF - I）或比目鱼肌（SOL）以及趾长伸肌（EDL）的质量或功能方面未观察到差异。腰椎（L1 - 4）区域的高分辨率双能X线吸收测定扫描显示，全身振动组的BMC（0.33±0.05克对0.26±0.03克，P < 0.01）和BMD（0.21±0.01克/平方厘米对0.19±0.01克/平方厘米，P < 0.01）显著高于对照组。各组之间在食物摄入量上未观察到差异。
这些研究结果表明，全身振动减少了体脂积累和血清瘦素，而不影响全身的BMC、BMD或瘦体重。然而，椎体BMC和BMD的增加表明振动可能导致局部骨量和骨密度增加。此外，全身振动不影响肌肉功能或食物摄入量。
