Colzato Lorenza S, Slagter Heleen A, Spapé Michiel M A, Hommel Bernhard
Leiden University, Cognitive Psychology Unit & Leiden Institute for Brain and Cognition, Leiden, The Netherlands.
Neuropsychologia. 2008 Nov;46(13):3179-83. doi: 10.1016/j.neuropsychologia.2008.07.006. Epub 2008 Jul 16.
The Attentional Blink (AB)--a deficit in reporting the second of two target stimuli presented in close succession in a rapid sequence of distracters--has been related to individual processing limitations of working memory. Given the known role of dopamine (DA) in working memory processes, the present experiment tested the hypothesis that DA, and in particular the DA/D1 subsystem, plays a role in the AB. We present evidence that the spontaneous eyeblink rate (EBR), a functional marker of central dopaminergic function, reliably predicts the size of AB. Thus, in line with our hypothesis, these data point to a modulatory role for DA in the AB.
注意瞬脱（AB）——在快速呈现的一串干扰刺激中，难以报告紧挨着呈现的两个目标刺激中的第二个——与工作记忆的个体加工局限有关。鉴于多巴胺（DA）在工作记忆过程中的已知作用，本实验检验了DA尤其是DA/D1子系统在AB中发挥作用的假设。我们提供的证据表明，作为中枢多巴胺能功能的一个功能标记，自发眨眼率（EBR）能可靠地预测AB的大小。因此，与我们的假设一致，这些数据表明DA在AB中具有调节作用。
