Dalton Susanne Oksbjerg, Steding-Jessen Marianne, Gislum Mette, Frederiksen Kirsten, Engholm Gerda, Schüz Joachim
Institute of Cancer Epidemiology, Danish Cancer Society, Strandboulevarden 49, DK-2100 Copenhagen Ø, Denmark.
Eur J Cancer. 2008 Sep;44(14):1938-49. doi: 10.1016/j.ejca.2008.06.010. Epub 2008 Aug 4.
The purpose of this register-based study was to identify variations in cancer incidence and survival after cancer in Denmark on the basis of a range of socioeconomic, demographic and health-related indicators. The indicators were level of education, disposable income, affiliation to the work market, social class, housing tenure, size of dwelling, cohabitation status, type of district, ethnicity, Charlson comorbidity index, depression and schizophrenia measured at the individual level on an annual basis. The study population comprised all Danish residents born between 1925 and 1973 and aged >or=30 years, who were followed up for cancer incidence in 1994-2003 and for survival in 1994-2006. The study was based on 3.22 million persons, yielding almost 26 million person-years and 147,973 cancers. In this paper, we provide a detailed description of the indicators and the statistical methods, and we discuss the strengths and limitations of our approach.
这项基于登记资料的研究旨在根据一系列社会经济、人口统计学和健康相关指标，确定丹麦癌症发病率和癌症确诊后的生存率差异。这些指标包括教育水平、可支配收入、就业市场从属情况、社会阶层、住房保有形式、居住面积、同居状况、地区类型、种族、查尔森合并症指数、抑郁和精神分裂症，每年在个体层面进行测量。研究人群包括所有出生于1925年至1973年且年龄≥30岁的丹麦居民，对其在1994 - 2003年进行癌症发病率随访，并在1994 - 2006年进行生存率随访。该研究基于322万人，产生了近2600万人年的数据以及147973例癌症病例。在本文中，我们详细描述了这些指标和统计方法，并讨论了我们研究方法的优点和局限性。
