Lee Seon Yeong, Gallagher Dympna
Body Composition Unit, Obesity Research Center, St. Luke's-Roosevelt Hospital, Columbia University, New York, New York, USA.
Curr Opin Clin Nutr Metab Care. 2008 Sep;11(5):566-72. doi: 10.1097/MCO.0b013e32830b5f23.
The present study reviews the most recently developed and commonly used methods for the determination of human body composition in vivo with relevance for nutritional assessment.
Body composition measurement methods are continuously being perfected with the most commonly used methods being bioelectrical impedance analysis, dilution techniques, air displacement plethysmography, dual energy X-ray absorptiometry, and MRI or magnetic resonance spectroscopy. Recent developments include three-dimensional photonic scanning and quantitative magnetic resonance. Collectively, these techniques allow for the measurement of fat, fat-free mass, bone mineral content, total body water, extracellular water, total adipose tissue and its subdepots (visceral, subcutaneous, and intermuscular), skeletal muscle, select organs, and ectopic fat depots.
There is an ongoing need to perfect methods that provide information beyond mass and structure (static measures) to kinetic measures that yield information on metabolic and biological functions. On the basis of the wide range of measurable properties, analytical methods and known body composition models, clinicians and scientists can quantify a number of body components and with longitudinal assessment, can track changes in health and disease with implications for understanding efficacy of nutritional and clinical interventions, diagnosis, prevention, and treatment in clinical settings. With the greater need to understand precursors of health risk beginning in childhood, a gap exists in appropriate in-vivo measurement methods beginning at birth.
本研究回顾了最近开发的和常用的用于体内人体成分测定的方法,这些方法与营养评估相关。
人体成分测量方法在不断完善,最常用的方法包括生物电阻抗分析、稀释技术、空气置换体积描记法、双能X线吸收法以及MRI或磁共振波谱法。最近的进展包括三维光子扫描和定量磁共振。总体而言,这些技术能够测量脂肪、去脂体重、骨矿物质含量、全身水、细胞外液、总脂肪组织及其亚库(内脏、皮下和肌间)、骨骼肌、特定器官以及异位脂肪库。
目前仍需要完善方法,从提供质量和结构信息(静态测量)的方法发展到能提供代谢和生物学功能信息的动力学测量方法。基于广泛的可测量特性、分析方法和已知的人体成分模型,临床医生和科学家可以量化多种身体成分,通过纵向评估,可以追踪健康和疾病的变化,这对于理解营养和临床干预的疗效、临床诊断、预防和治疗具有重要意义。由于更需要从儿童时期就了解健康风险的先兆,从出生开始就缺乏合适的体内测量方法。