Galante J O, Lemons J, Spector M, Wilson P D, Wright T M
Department of Orthopedic Surgery, Rush-Presbyterian-St. Luke's, Chicago, Illinois.
J Orthop Res. 1991 Sep;9(5):760-75. doi: 10.1002/jor.1100090516.
The interaction between implant materials and the surrounding biological environment continues to be an area of intense research and clinical interest. This article presents the information presented in a symposium, held during the 36th Annual Meeting of the Orthopaedic Research Society, in which several important issues concerning the biologic effects of implant materials were discussed. These issues included the mechanisms by which implant materials are released to the surrounding tissues and the ways in which these tissues respond to implant materials. The problem of bone loss around cementless implants was discussed as a specific example of a biologic effect resulting in both bone remodelling and endosteal erosion.
植入材料与周围生物环境之间的相互作用一直是深入研究和临床关注的领域。本文介绍了在骨科研究学会第36届年会上举行的一次研讨会上所呈现的信息，其中讨论了有关植入材料生物学效应的几个重要问题。这些问题包括植入材料释放到周围组织的机制以及这些组织对植入材料的反应方式。无骨水泥植入物周围的骨丢失问题作为导致骨重塑和骨内膜侵蚀的生物学效应的一个具体例子进行了讨论。
