Sahu Abhishek, Goswami Pranab, Bora Utpal
Department of Biotechnology, Indian Institute of Technology Guwahati, Guwahati, 781039, Assam, India.
J Mater Sci Mater Med. 2009 Jan;20(1):171-5. doi: 10.1007/s10856-008-3549-4. Epub 2008 Aug 14.
Chitosan is synthesized by deacetylating chitin with NaOH solution under microwave irradiation. The process describes a rapid synthesis procedure in comparison to conventional methods. The microwave-synthesized chitosan was characterized by Ninhydrin test, Fourier transform-infrared spectroscopy and X-ray diffraction measurements. The experimental results show that the degree of deacetylation increased with increasing irradiation time. A degree of deacetylation of 85.3% was achieved after irradiating chitin with 45% NaOH solution in a microwave for 5.5 min at 900-watt power. This method can be very useful for synthesizing low molecular weight chitosan with rapid and clean chemistry.
壳聚糖是在微波辐射下用氢氧化钠溶液对几丁质进行脱乙酰化反应合成的。与传统方法相比，该过程描述了一种快速合成程序。通过茚三酮试验、傅里叶变换红外光谱和X射线衍射测量对微波合成的壳聚糖进行了表征。实验结果表明，脱乙酰度随辐射时间的增加而提高。在900瓦功率下，用45%的氢氧化钠溶液在微波中辐照几丁质5.5分钟后，脱乙酰度达到85.3%。该方法对于快速、清洁地合成低分子量壳聚糖可能非常有用。
