Soy Mehmet, Karaca Nuran, Umit Elif Uğur, Bes Cemal, Piskin Süleyman
Department of Internal Medicine, Rheumatology, Faculty of Medicine, Abant Izzet Baysal University, 14100, Gölköy, Bolu, Turkey.
Rheumatol Int. 2008 Dec;29(2):223-5. doi: 10.1007/s00296-008-0686-5. Epub 2008 Aug 15.
Psoriatic arthritis is an autoimmune, chronic, systemic inflammatory disorder characterized by the association of arthritis with psoriasis. In this paper, we explore the characteristics of joint and nail involvement in Turkish patients with psoriatic arthritis. Forty patients with psoriasis (M/F, 18/22) and 49 (M/F, 25/24) subjects with psoriatic arthritis were included in the study. Clinical characteristics of the patients were recorded. The distribution of the subjects with arthritis: (according to the clinical and radiological findings): polyarticular, 65%; oligoarticular, 23%; isolated axial involvement, 7.7%; arthritis mutilans, 3.8%; sacroiliitis, 19%. Nail involvement was significantly higher among patients with arthritis; i.e., 91 versus 32%; (P<0.05). There were no correlation between the skin involvement pattern and the arthritis type (P>0.05). Nevertheless, no relation was observed between the psoriasis duration and arthritis (P>0.05). Nail involvement is a frequent feature of the psoriatic arthritis which may be a useful finding for differential diagnosis of psoriatic arthritis from other inflammatory arthropathies.
银屑病关节炎是一种自身免疫性、慢性、全身性炎症性疾病，其特征是关节炎与银屑病相关。在本文中，我们探讨了土耳其银屑病关节炎患者的关节和指甲受累特征。本研究纳入了40例银屑病患者（男/女，18/22）和49例银屑病关节炎患者（男/女，25/24）。记录了患者的临床特征。关节炎患者的分布情况（根据临床和放射学检查结果）：多关节型，65%；少关节型，23%；单纯轴向受累，7.7%；毁形性关节炎，3.8%；骶髂关节炎，19%。关节炎患者的指甲受累率显著更高，即91% 对32%；（P<0.05）。皮肤受累模式与关节炎类型之间无相关性（P>0.05）。然而，银屑病病程与关节炎之间未观察到相关性（P>0.05）。指甲受累是银屑病关节炎的常见特征，这可能是银屑病关节炎与其他炎性关节病鉴别诊断的有用发现。
