Larrabee Glenn J, Millis Scott R, Meyers John E
Clin Neuropsychol. 2008 Sep;22(5):813-25. doi: 10.1080/13854040701625846.
We compared the sensitivity to brain dysfunction of an ability focused neuropsychological battery (AFB), as a proxy for the core of a flexible battery, to the Halstead-Reitan Battery (HRB). The AFB was designed to represent constructs of language function, fine motor skill, working memory, processing speed, verbal and visual memory, and verbal and visual abstraction and problem solving. Receiver operating characteristic analysis (ROC) yielded an area under curve (AUC) of. 86 for the AFB, versus. 83 for the HRB (p =. 50), for discriminating 54 patients with brain dysfunction due to various etiologies, from 69 non-neurologic medical controls. Additionally, Bayesian Model Averaging selected four tests from the combined set of AFB and HRB subtests, plus Trail Making B, which optimally discriminated the brain dysfunction from medical control patients: H-Words, Grooved Pegboard, Finger Tapping, and Trail Making B. These data support the current mainstream practice in neuropsychology of using an AFB (flexible battery) to assess brain dysfunction. In particular, tests involving processing speed appear to be among the most sensitive measures of brain dysfunction. The data do not support the superiority of the HRB to AFB approaches.
我们将一种以能力为重点的神经心理成套测验（AFB）作为灵活成套测验核心的替代指标，与霍尔斯特德-赖坦成套测验（HRB）对脑功能障碍的敏感性进行了比较。AFB旨在代表语言功能、精细运动技能、工作记忆、处理速度、言语和视觉记忆以及言语和视觉抽象与问题解决等结构。接受者操作特征分析（ROC）得出，对于区分54例因各种病因导致脑功能障碍的患者与69例非神经科医学对照，AFB的曲线下面积（AUC）为0.86，而HRB为0.83（p = 0.50）。此外，贝叶斯模型平均法从AFB和HRB子测验的组合集中选择了四项测验，再加上连线测验B，这些测验能最佳地区分脑功能障碍患者与医学对照患者：H-单词、槽式钉板测验、手指敲击测验和连线测验B。这些数据支持了神经心理学中目前使用AFB（灵活成套测验）评估脑功能障碍的主流做法。特别是，涉及处理速度的测验似乎是脑功能障碍最敏感的测量指标之一。数据并不支持HRB方法优于AFB方法。
