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古老问题的进展。

Advances in age-old questions.

作者信息

Carlson Darby J, Pashaj Anjeza, Gardner Kylee, Carlson Kimberly A

机构信息

Biology Department, University of Nebraska at Kearney, Kearney, Nebraska, USA.

出版信息

Fly (Austin). 2008 May-Jun;2(3):149-51. doi: 10.4161/fly.6381. Epub 2008 May 29.

Abstract

Drosophila melanogaster is an ideal model organism for various types of aging studies. They are easy to maintain, relatively inexpensive, have short life cycles, provide large sample sizes, and can be genetically manipulated via various methods for testing. The 49(th) Annual Drosophila Research Conference, held in San Diego, CA (April 2-6, 2008), had over 30 poster presentations and eight platform talks devoted to physiology and aging, and seven presentations in a longevity and functional senescence workshop. The data presented via these avenues included life span manipulation, physiological related genes, candidate aging genes, gene expression, signaling, and using D. melanogaster as a model for age related disease, to name a few. This report provides highlights of some of the information presented in the poster, platform and workshop presentations.

摘要

黑腹果蝇是用于各类衰老研究的理想模式生物。它们易于饲养,成本相对较低,生命周期短,能提供大量样本,并且可以通过多种方法进行基因操作以用于测试。于2008年4月2日至6日在加利福尼亚州圣地亚哥举行的第49届果蝇研究年会,有30多个海报展示以及8个关于生理学和衰老的大会报告,还有在长寿与功能衰老研讨会上的7个报告。通过这些途径展示的数据包括寿命调控、生理相关基因、候选衰老基因、基因表达、信号传导,以及将黑腹果蝇用作与年龄相关疾病的模型等等。本报告突出介绍了海报展示、大会报告和研讨会报告中呈现的一些信息要点。

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