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土耳其成年人中高血压前期和高血压的患病率及相关危险因素:特拉布宗高血压研究

Prevalence of prehypertension and hypertension and associated risk factors among Turkish adults: Trabzon Hypertension Study.

作者信息

Erem Cihangir, Hacihasanoglu Arif, Kocak Mustafa, Deger Orhan, Topbas Murat

机构信息

Karadeniz Technical University, Faculty of Medicine, Department of Internal Medicine, Division of Endocrinology and Metabolism, The Trabzon Endocrinological Studies Group, Trabzon, Turkey.

出版信息

J Public Health (Oxf). 2009 Mar;31(1):47-58. doi: 10.1093/pubmed/fdn078. Epub 2008 Sep 30.

Abstract

BACKGROUND

To estimate the prevalence, awareness and control of prehypertension (preHT) and hypertension (HT) as defined by JNC-7 criteria in the Trabzon Region and its associations with demographic factors (age, sex, obesity, marital status, reproductive history in women and level of education), socioeconomic factors (household income and occupation), family history of selected medical conditions (diabetes, hypertension, obesity and cardiovascular disease), lifestyle factors (smoking habits, physical activity and alcohol consumption) in the adult population.

METHODS

In this cross-sectional survey, a sample of households was systematically selected from the central province of Trabzon and its nine towns. A total of 4809 adult subjects (2601 women and 2208 men) were included in the study. Demographic and socioeconomic factors, family history of selected medical conditions, and lifestyle factors were obtained for all participants. Systolic blood pressure (BP) and diastolic BP levels were measured for all subjects. The persons included in the questionnaire were invited to the local medical centers for blood examination between 08:00-10:00 following 12 hours of fasting. The levels of serum glucose (FBG), total cholesterol (Total-C), high density cholesterol (HDL-C), low density cholesterol (LDL-C) and triglycerides were measured with autoanalyzer. Definition and classification of HT was performed according to guidelines from the US JNC-7 report. Prevalence, awareness, treatment and control of HT were assessed.

RESULTS

The prevalences of HT and preHT were 44.0% (46.1% in women and 41.6% in men) and 14.5% (12.6% in women and 16.8% in men), respectively. Overall, only 41% of the hypertensive individuals had been previously diagnosed. Furthermore, 54.5% of the hypertensive subjects were being treated with antihypertensive drugs (AHD), but only 24.3% of treated subjects had their BP adequately controlled. Among all hypertensive subjects (known and newly diagnosed), only 5.43% had their BP under control. The prevalence of HT increased with age, being highest in the 60- to 69-year-old age group (84.4%) but lower again in the 70+ age group. Interestingly, the prevalence was 16.9% in the 20-to 29-year old age group. HT was associated positively with marital status, parity, cessation of cigarette smoking, and negatively with level of education, alcohol consumption, current cigarette use, and physical activity. Multinomial logistic regression analysis revealed that HT were significantly associated with age, male gender, BMI, low education level, nonsmoking, positive family history of selected medical conditions, occupation, and parity.

CONCLUSIONS

The Trabzon Hypertension Study data indicated that HT is very common and is an important health problem in the adult population of Trabzon. Patients who are unaware of their status and treated uncontrolled hypertensives are at high risk of early cardiovascular morbidity and mortality. To control preHT and HT, effective public health education and urgent precautions are needed. The precautions include serious health education, a well-balanced diet and increasing physical activity.

摘要

背景

根据美国国家高血压教育计划(JNC)-7标准,评估特拉布宗地区成人中高血压前期(preHT)和高血压(HT)的患病率、知晓率及控制情况,以及这些情况与人口统计学因素(年龄、性别、肥胖、婚姻状况、女性生育史和教育程度)、社会经济因素(家庭收入和职业)、特定疾病家族史(糖尿病、高血压、肥胖和心血管疾病)、生活方式因素(吸烟习惯、体育活动和饮酒)之间的关联。

方法

在这项横断面调查中,从特拉布宗中心省份及其九个城镇系统选取家庭样本。共有4809名成年受试者(2601名女性和2208名男性)纳入研究。收集了所有参与者的人口统计学和社会经济因素、特定疾病家族史以及生活方式因素。测量了所有受试者的收缩压(BP)和舒张压水平。问卷纳入的人员在禁食12小时后的08:00 - 10:00被邀请到当地医疗中心进行血液检查。使用自动分析仪测量血清葡萄糖(FBG)、总胆固醇(Total-C)、高密度胆固醇(HDL-C)、低密度胆固醇(LDL-C)和甘油三酯水平。根据美国JNC - 7报告指南对HT进行定义和分类。评估HT的患病率、知晓率、治疗率和控制率。

结果

HT和preHT的患病率分别为44.0%(女性为46.1%,男性为41.6%)和14.5%(女性为12.6%,男性为16.8%)。总体而言,仅有41%的高血压个体之前被诊断过。此外,54.5%的高血压受试者正在接受降压药物(AHD)治疗,但只有24.3%的治疗受试者血压得到充分控制。在所有高血压受试者(已知和新诊断的)中,仅有5.43%的血压得到控制。HT的患病率随年龄增加而上升,在60 - 69岁年龄组最高(84.4%),但在70岁及以上年龄组再次降低。有趣的是,在20 - 29岁年龄组患病率为16.9%。HT与婚姻状况、产次、戒烟呈正相关,与教育程度、饮酒、当前吸烟和体育活动呈负相关。多项逻辑回归分析显示,HT与年龄、男性性别、体重指数、低教育水平、不吸烟、特定疾病家族史阳性、职业和产次显著相关。

结论

特拉布宗高血压研究数据表明,HT在特拉布宗成年人群中非常普遍,是一个重要的健康问题。未意识到自身状况的患者以及血压控制不佳的高血压患者早期发生心血管疾病和死亡的风险很高。为了控制preHT和HT,需要有效的公共卫生教育和紧急预防措施。这些预防措施包括认真的健康教育、均衡饮食和增加体育活动。

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