Fisher Jeffrey D, Amico K Rivet, Fisher William A, Harman Jennifer J
Center for Health, Intervention, and Prevention (CHIP), University of Connecticut, 2006 Hillside Road, Unit 1248, Storrs, CT 06269, USA.
Curr HIV/AIDS Rep. 2008 Nov;5(4):193-203. doi: 10.1007/s11904-008-0028-y.
Suboptimal adherence to highly active antiretroviral therapy (HAART) may have serious consequences for HIV patients, and for public health overall. The Information-Motivation-Behavioral Skills (IMB) model of HAART adherence can be used to understand the dynamics of HAART adherence and to intervene with patients to promote more optimal levels of adherence. This article reviews the core hypotheses of the IMB model of HAART adherence and describes available correlational and experimental evaluations of the model, outcomes of adherence intervention trials that applied the model, and IMB model-based interventions that are currently under evaluation. It then explores one potential promising application of the model that uses a protocol originally developed and demonstrated as a structured patient-centered, provider-delivered risk reduction intervention to deliver information, motivation, and behavioral skills-based adherence-promotion strategies. This protocol could be incorporated into clinical practice as a valuable tool in working with patients individually.
对抗逆转录病毒疗法（HAART）依从性欠佳可能会给艾滋病毒患者以及整体公共卫生带来严重后果。HAART依从性的信息-动机-行为技能（IMB）模型可用于理解HAART依从性的动态变化，并对患者进行干预，以促进更高水平的依从性。本文回顾了HAART依从性IMB模型的核心假设，描述了该模型现有的相关性和实验性评估、应用该模型的依从性干预试验结果，以及目前正在评估的基于IMB模型的干预措施。然后探讨了该模型一个潜在的有前景的应用，即使用最初开发并证明是一种结构化的以患者为中心、由医护人员提供的降低风险干预措施的方案，来提供基于信息、动机和行为技能的依从性促进策略。该方案可作为与患者个体合作的宝贵工具纳入临床实践。
