Liem Eryn T, Sauer Pieter J J, Oldehinkel Albertine J, Stolk Ronald P
Department of Pediatrics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
Arch Pediatr Adolesc Med. 2008 Oct;162(10):981-8. doi: 10.1001/archpedi.162.10.981.
To present an overview of the association between depressive symptoms in childhood and adolescence and subsequent overweight in later life.
MEDLINE, EMBASE, and Web of Science for all indexed journals from January 1, 1997, to May 30, 2007.
Abstracts of 513 articles were reviewed manually. Studies were excluded if unrelated to depressive symptoms and overweight (n = 460), if they were conducted in an adult population (n = 10) or in a population of all age groups (n = 2), or if they were performed in clinic-based populations of overweight participants. In total, 32 articles were reviewed including 21 cross-sectional and 11 longitudinal reports. Main Exposure Depressive symptoms in childhood and adolescence. Main Outcome Measure Overweight.
Four cross-sectional studies that satisfied our quality criteria revealed an association between depressive symptoms and overweight in girls aged 8 to 15 years, reporting different effect sizes including a correlation coefficient of 0.14 and a regression coefficient of 0.27. Four longitudinal studies in accord with our quality criteria suggest that depressive symptoms in childhood or adolescence are associated with a 1.90- to 3.50-fold increased risk of subsequent overweight (95% confidence intervals varying from 1.02 to 5.80, respectively).
These results support a positive association between depressive symptoms at age 6 to 19 years and overweight in later life, assessed after a period of 1 to 15 years.
概述儿童期和青少年期的抑郁症状与成年后期超重之间的关联。
1997年1月1日至2007年5月30日期间所有被索引期刊的MEDLINE、EMBASE和科学网。
人工查阅了513篇文章的摘要。如果与抑郁症状和超重无关（n = 460）、在成年人群体中进行（n = 10）或在所有年龄组人群中进行（n = 2），或者在超重参与者的临床人群中进行，则排除这些研究。总共查阅了32篇文章，包括21篇横断面报告和11篇纵向报告。主要暴露因素为儿童期和青少年期的抑郁症状。主要结局指标为超重。
四项符合我们质量标准的横断面研究显示，8至15岁女孩的抑郁症状与超重之间存在关联，报告的效应大小不同，包括相关系数为0.14和回归系数为0.27。四项符合我们质量标准的纵向研究表明，儿童期或青少年期的抑郁症状与随后超重的风险增加1.90至3.50倍相关（95%置信区间分别从1.02到5.80不等）。
这些结果支持6至19岁时的抑郁症状与成年后期超重之间存在正相关，这是在1至15年的时间段后评估得出的。
