Bennett Jason W, Herrera Monica L, Lewis James S, Wickes Brian W, Jorgensen James H
San Antonio Military Medical Center, Fort Sam Houston, Texas 782341, USA.
Antimicrob Agents Chemother. 2009 Jan;53(1):292-4. doi: 10.1128/AAC.00931-08. Epub 2008 Oct 13.
Carbapenemases are among the newest resistance mechanisms to emerge in some gram-negative bacteria. We describe bacteremia in a critically ill liver transplant recipient infected with KPC-2-producing Enterobacter cloacae and Pseudomonas putida. Although this enzyme has been previously described in Enterobacter spp., this is the first report of KPC carbapenemase in P. putida.
碳青霉烯酶是一些革兰氏阴性菌中最新出现的耐药机制之一。我们描述了一名重症肝移植受者发生的菌血症,该患者感染了产KPC-2的阴沟肠杆菌和恶臭假单胞菌。尽管这种酶此前已在肠杆菌属中被描述,但这是恶臭假单胞菌中KPC碳青霉烯酶的首次报道。