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意大利一名肿瘤血液科儿科患者发生首例产类VIM-1菌血症。

First Case of VIM-1-like-Producing Bacteremia in an Oncohematological Pediatric Patient in Italy.

作者信息

Cortazzo Venere, Agosta Marilena, Gaspari Stefania, Vrenna Gianluca, Lucignano Barbara, Onori Manuela, Di Ruscio Valentina, Mancinelli Livia, Domo Danielle, Perno Carlo Federico, Bernaschi Paola

机构信息

Microbiology and Diagnostic Immunology Unit, Department of Diagnostic and Laboratory Medicine, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.

Department of Hematology/Oncology, Cell and Gene Therapy, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.

出版信息

Antibiotics (Basel). 2023 Jun 9;12(6):1033. doi: 10.3390/antibiotics12061033.

DOI:10.3390/antibiotics12061033
PMID:37370352
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10295762/
Abstract

Bacterial infections caused by multidrug-resistant (MDR) Gram-negatives are of great concern worldwide, as they are frequently associated with high mortality and morbidity rates. To date, two cases of VIM-2 metallo-β-lactamase (MBL)-producing bacteremia have been ever reported in France and Spain between 2004 and 2010. Here, we present the first case of VIM-1-like-producing isolated in blood culture collected from an oncohematological pediatric patient admitted to Bambino Gesù Children's Hospital (IRCCS) in Rome, Italy.

摘要

耐多药（MDR）革兰氏阴性菌引起的细菌感染在全球范围内备受关注，因为它们常常与高死亡率和高发病率相关。迄今为止，2004年至2010年间，法国和西班牙曾报告过两例产VIM-2金属β-内酰胺酶（MBL）的菌血症病例。在此，我们报告首例从意大利罗马的 Bambino Gesù儿童医院（IRCCS）收治的一名儿科肿瘤血液病患者血培养中分离出的产VIM-1样酶的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ae4/10295762/1940980d011b/antibiotics-12-01033-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ae4/10295762/3351c1e83330/antibiotics-12-01033-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ae4/10295762/b391e0e61c48/antibiotics-12-01033-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ae4/10295762/1940980d011b/antibiotics-12-01033-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ae4/10295762/3351c1e83330/antibiotics-12-01033-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ae4/10295762/b391e0e61c48/antibiotics-12-01033-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ae4/10295762/1940980d011b/antibiotics-12-01033-g003.jpg

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