Nair Rathish, Kalariya Tamanna, Chanda Sumitra
Department of Biosciences, Saurashtra University, Rajkot, Gujarat, India.
J Herb Pharmacother. 2007;7(3-4):191-201. doi: 10.1080/15228940802152836.
In the present work, selected plants were screened for their potential antibacterial activity. For evaluating antibacterial activity, both aqueous and organic solvent methanol was used. The plants screened were Ocimum sanctum, Jatropha gossypifolia, Boerhavia diffusa, Azadirachta indica, Solidago virgaurea, and Commelina benghalensis. The antibacterial activity was assessed against six bacterial strains--Pseudomonas testosteroni, Staphylococcus epidermidis, Klebsiella pneumoniae, Bacillus subtilis, Proteus morganii, Micrococcus flavus. Agar disc diffusion method and Agar ditch diffusion method were used to study the antibacterial activity of all these plants. Ps. testosteroni and K. pneumoniae were the most resistant bacterial strains. A. indica showed strong activity against tested bacterial strains. Therefore, we conclude that A. indica may prove to be a promising agent, and further exploration into this compound should be performed to determine its full therapeutic potential. In addition, its leaf extract can also be used as a lead molecule in combating the diseases caused by the studied bacterial strains.
在本研究中，对选定的植物进行了潜在抗菌活性筛选。为评估抗菌活性，使用了水和有机溶剂甲醇。所筛选的植物有圣罗勒、棉叶麻风树、胀果博落回、印楝、高山一枝黄花和孟加拉鸭跖草。针对六种细菌菌株——睾丸酮假单胞菌、表皮葡萄球菌、肺炎克雷伯菌、枯草芽孢杆菌、摩根变形杆菌、微黄微球菌评估抗菌活性。采用琼脂平板扩散法和琼脂沟扩散法研究所有这些植物的抗菌活性。睾丸酮假单胞菌和肺炎克雷伯菌是最具抗性的细菌菌株。印楝对受试细菌菌株表现出较强活性。因此，我们得出结论，印楝可能被证明是一种有前景的药剂，应对该化合物进行进一步探索以确定其全部治疗潜力。此外，其叶提取物也可用作对抗由所研究细菌菌株引起疾病的先导分子。
