Marchese Andrew D, Chipman Daniel, de la Oliva Pedro, Kacmarek Robert M
Respiratory Care Massachusetts General Hospital, Boston, MA 02114, USA.
Intensive Care Med. 2009 Apr;35(4):631-8. doi: 10.1007/s00134-008-1332-0. Epub 2008 Oct 18.
Traditionally, specific ventilators have been manufactured to only provide neonatal mechanical ventilation. However, many of the current generation of ICU ventilators also include a neonatal mode.
Using the IngMar ASL5000 lung simulator the Puritan Bennett 840, the Maquet Servo i, the Viasys AVEA, the GE Engström, the Drager Evita XL and Babylog 8000 Plus were evaluated during assisted ventilation in the pressure assist/control mode. Three lung mechanics were set: resistance 50 cmH(2)O/L/s, compliance 2 mL/cmH(2)O; resistance 100 cmH(2)O/L/s, compliance 1 mL/cmH(2)O; and resistance 150 cmH(2)O/L/s, compliance 0.5 mL/cmH(2)O. A maximum negative pressure drop of 4 and 7 cmH(2)O was achieved during simulated inspirations. Each ventilator was evaluated with PEEP 5 cmH(2)O, peak pressure 20 cmH(2)O and inspiratory time 0.3 s and with PEEP 10 cmH(2)O, peak pressure 30 cmH(2)O and inspiratory time 0.4 s. Each ventilator setting was then repeated with a leak of 0.3 L/min at a constant pressure of 5 cmH(2)O.
Overall each of the 5 ICU ventilators responded faster or greater than the Babylog with respect to: pressure to trigger (except the Servo i), time to trigger (except the Evita XL), time between trigger and return of pressure to baseline, time from start of breath to 90% of peak pressure (except the Avea) and pressure time product of breath activation. Expiratory tidal volume was also greater with all ICU ventilators except the Avea. Variation in mechanics, leak, PEEP and muscular effort had little effect on these differences.
All ICU ventilators tested were able to at least equal the performance of the Babylog 8000 Plus on all variables evaluated.
传统上,特定的呼吸机仅用于提供新生儿机械通气。然而,当前一代的许多重症监护病房(ICU)呼吸机也包含新生儿模式。
使用英格玛ASL5000肺模拟器,在压力辅助/控制模式下的辅助通气过程中,对伟康840、迈柯唯Servo i、维赛思AVE A、通用电气Engström、德尔格Evita XL和Babylog 8000 Plus进行评估。设置了三种肺力学参数:阻力50 cmH₂O/L/s,顺应性2 mL/cmH₂O;阻力100 cmH₂O/L/s,顺应性1 mL/cmH₂O;阻力150 cmH₂O/L/s,顺应性0.5 mL/cmH₂O。在模拟吸气过程中,实现了最大4 cmH₂O和7 cmH₂O的负压降。每个呼吸机在呼气末正压(PEEP)为5 cmH₂O、峰值压力为20 cmH₂O、吸气时间为0.3 s的条件下进行评估,以及在PEEP为10 cmH₂O、峰值压力为30 cmH₂O、吸气时间为0.4 s的条件下进行评估。然后在5 cmH₂O的恒定压力下,以0.3 L/min的漏气量重复每个呼吸机设置。
总体而言,在以下方面,5台ICU呼吸机中的每一台的响应速度都比Babylog更快或更大:触发压力(Servo i除外)、触发时间(Evita XL除外)、触发与压力恢复到基线之间的时间、从呼吸开始到达到峰值压力的90%的时间(AVE A除外)以及呼吸激活的压力时间乘积。除AVE A外,所有ICU呼吸机的呼气潮气量也更大。力学参数、漏气、PEEP和肌肉用力的变化对这些差异影响很小。
所有测试的ICU呼吸机在所有评估变量上的表现至少与Babylog 8000 Plus相当。