Matthews K R, Harmon R J, Langlois B E
Department of Animal Sciences, University of Kentucky, Lexington 40546-0215.
J Dairy Sci. 1991 Jun;74(6):1855-9. doi: 10.3168/jds.S0022-0302(91)78350-1.
Microbiological data from 1123 uninfected quarters and 216 quarters with preexisting coagulase-negative staphylococci infections were analyzed to determine the influence of infection status on subsequent new infection rate. Overall, prevalence of new infections in uninfected quarters was approximately two times that in quarters already harboring a coagulase-negative Staphylococcus infection. New infections by coagulase-negative staphylococci were greater in uninfected quarters than in quarters with preexisting coagulase-negative staphylococci infections. However, no differences were observed between uninfected and infected quarters in number of new infections by major pathogens (Staphylococcus aureus, streptococci, and coliforms). No differences were observed in uninfected or coagulase-negative Staphylococcus-infected quarters in infections with minor pathogens compared with major pathogens. The influence of individual coagulase-negative Staphylococcus species on new infections was also analyzed. However, numbers of existing infections by Staphylococcus species other than Staphylococcus chromogenes were limited. Therefore, the protective capacity of each coagulase-negative Staphylococcus species was difficult to assess. Overall, a significant restriction of bacterial invasion was observed in quarters with a preexisting infection. These results suggest that quarters harboring a coagulase-negative Staphylococcus infection suppress colonization of the mammary gland by mastitis-causing pathogens.
对来自1123个未感染乳腺区和216个已存在凝固酶阴性葡萄球菌感染的乳腺区的微生物学数据进行分析，以确定感染状态对后续新感染率的影响。总体而言，未感染乳腺区新感染的发生率约为已存在凝固酶阴性葡萄球菌感染的乳腺区的两倍。凝固酶阴性葡萄球菌引起的新感染在未感染乳腺区比在已存在凝固酶阴性葡萄球菌感染的乳腺区更多。然而，在主要病原体（金黄色葡萄球菌、链球菌和大肠菌群）引起的新感染数量方面，未感染和感染乳腺区之间未观察到差异。与主要病原体相比，在未感染或凝固酶阴性葡萄球菌感染的乳腺区中，次要病原体感染情况未观察到差异。还分析了单个凝固酶阴性葡萄球菌种类对新感染的影响。然而，除产色葡萄球菌外的其他葡萄球菌种类的现有感染数量有限。因此，每种凝固酶阴性葡萄球菌种类的保护能力难以评估。总体而言，在已存在感染的乳腺区观察到细菌入侵受到显著限制。这些结果表明，存在凝固酶阴性葡萄球菌感染的乳腺区可抑制引起乳腺炎的病原体在乳腺中的定植。
