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来自在地中海沿岸和大西洋沿岸野生生长的胡萝卜(Daucus carota L. subsp. carota)的精油的化学特征及生物活性

Chemical characterization and biological activity of essential oils from Daucus carota L. subsp. carota growing wild on the Mediterranean coast and on the Atlantic coast.

作者信息

Maxia Andrea, Marongiu Bruno, Piras Alessandra, Porcedda Silvia, Tuveri Enrica, Gonçalves Maria J, Cavaleiro Carlos, Salgueiro Ligia

机构信息

Dipartimento di Scienze Botaniche and Co.S.Me.Se, Università degli Studi di Cagliari, Viale Sant'Ignazio, I-09123 Cagliari, Italy.

出版信息

Fitoterapia. 2009 Jan;80(1):57-61. doi: 10.1016/j.fitote.2008.09.008. Epub 2008 Oct 8.

DOI:10.1016/j.fitote.2008.09.008
PMID:18950693
Abstract

The essential oils and supercritical CO(2) extracts of wild Daucus carota L. subsp. carota growing spontaneously in Sardinia and in Portugal were investigated. The main components in the Sardinian essential oil of flowering and mature umbels with seeds are beta-bisabolene (17.6-51.0%) and 11-alpha-(H)-himachal-4-en-1-beta-ol (9.0-21.6%); instead, the oils from Portuguese samples are predominantly composed of geranyl acetate (5.2-65.0%) and alpha-pinene (3.5-37.9%). Supercritical extracts contain lower amounts of monoterpenes and higher amounts of sesquiterpene hydrocarbons. Antifungal activities of the Sardinian oils were the highest, particularly for dermatophytes and Cryptococcus neoformans, with MIC values of 0.16-0.64 microL mL(-1).

摘要

对在撒丁岛和葡萄牙自然生长的野生胡萝卜(Daucus carota L. subsp. carota)的精油和超临界CO₂提取物进行了研究。撒丁岛开花且带有种子的成熟伞形花序的精油中的主要成分是β-红没药烯(17.6 - 51.0%)和11-α-(H)-喜马拉雅-4-烯-1-β-醇(9.0 - 21.6%);相反,葡萄牙样品的精油主要由乙酸香叶酯(5.2 - 65.0%)和α-蒎烯(3.5 - 37.9%)组成。超临界提取物中含有较低含量的单萜类化合物和较高含量的倍半萜烃类化合物。撒丁岛精油的抗真菌活性最高,特别是对皮肤癣菌和新型隐球菌,其最低抑菌浓度(MIC)值为0.16 - 0.64微升/毫升。

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