非洲爪蟾胚胎发育过程中soxB2基因（sox14和sox21）的克隆与发育表达
Cloning and developmental expression of the soxB2 genes, sox14 and sox21, during Xenopus laevis embryogenesis.
作者信息
Cunningham Doreen D, Meng Zhuo, Fritzsch Bernd, Casey Elena Silva
机构信息
Georgetown University, Department of Biology, Washington, DC 20057, USA.
出版信息
Int J Dev Biol. 2008;52(7):999-1004. doi: 10.1387/ijdb.082586dc.
Abstract
The Sox family of transcription factors is thought to regulate gene expression in a wide variety of developmental processes. Here we describe the cloning of the X. laevis orthologs of the SoxB2 family of transcription factors, sox14 and sox21. In situ hybridization revealed that sox14 expression is restricted to the hypothalamus, dorsal thalamus, the optic tectum, a region of the somatic motornucleus in the midbrain and hindbrain, the vestibular nuclei in the hindbrain and a discrete ventral domain in the developing spinal cord. In contrast to the limited expression domain of sox14, sox21 is found throughout the developing central nervous system, including the olfactory placodes, with strongest expression at the boundary between the midbrain and hindbrain.
摘要
转录因子Sox家族被认为在多种发育过程中调节基因表达。在此，我们描述了非洲爪蟾转录因子SoxB2家族直系同源基因sox14和sox21的克隆。原位杂交显示，sox14的表达局限于下丘脑、背侧丘脑、视顶盖、中脑和后脑躯体运动核的一个区域、后脑的前庭核以及发育中的脊髓中的一个离散腹侧区域。与sox14有限的表达域不同，sox21在整个发育中的中枢神经系统中都有发现，包括嗅基板，在中脑和后脑之间的边界处表达最强。
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2
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3
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