Khetsuriani Nino, Lu Xiaoyan, Teague W Gerald, Kazerouni Neely, Anderson Larry J, Erdman Dean D
Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA.
Emerg Infect Dis. 2008 Nov;14(11):1793-6. doi: 10.3201/eid1411.080386.
To determine links between human rhinoviruses (HRV) and asthma, we used data from a case-control study, March 2003-February 2004, among children with asthma. Molecular characterization identified several likely new HRVs and showed that association with asthma exacerbations was largely driven by HRV-A and a phylogenetically distinct clade of 8 strains, genogroup C.
为了确定人鼻病毒(HRV)与哮喘之间的联系,我们使用了2003年3月至2004年2月一项针对哮喘儿童的病例对照研究的数据。分子特征分析确定了几种可能的新型HRV,并表明与哮喘加重的关联主要由HRV-A以及一个由8个毒株组成的系统发育上不同的进化枝C型基因群驱动。