Barch Deanna M, Berman Marc G, Engle Randy, Jones Jessica Hurdelbrink, Jonides John, Macdonald Angus, Nee Derek Evan, Redick Thomas S, Sponheim Scott R
Department of Psychology, Washington University, St Louis, MO 63130, USA.
Schizophr Bull. 2009 Jan;35(1):136-52. doi: 10.1093/schbul/sbn153. Epub 2008 Nov 5.
The third meeting of the Cognitive Neuroscience Treatment Research to Improve Cognition in Schizophrenia (CNTRICS) was focused on selecting promising measures for each of the cognitive constructs selected in the first CNTRICS meeting. In the domain of working memory, the 2 constructs of interest were goal maintenance and interference control. CNTRICS received 3 task nominations for each of these constructs, and the breakout group for working memory evaluated the degree to which each of these tasks met prespecified criteria. For goal maintenance, the breakout group for working memory recommended the AX-Continuous Performance Task/Dot Pattern Expectancy task for translation for use in clinical trial contexts in schizophrenia research. For interference control, the breakout group recommended the recent probes and operation/symmetry span tasks for translation for use in clinical trials. This article describes the ways in which each of these tasks met the criteria used by the breakout group to recommend tasks for further development.
改善精神分裂症认知的认知神经科学治疗研究(CNTRICS)第三次会议聚焦于为第一次CNTRICS会议选定的每种认知结构选择有前景的测量方法。在工作记忆领域,两个感兴趣的结构是目标维持和干扰控制。CNTRICS就这些结构中的每一个收到了3项任务提名,工作记忆分组对这些任务中每一项符合预先设定标准的程度进行了评估。对于目标维持,工作记忆分组推荐将AX连续操作任务/点模式预期任务用于翻译,以用于精神分裂症研究的临床试验环境。对于干扰控制,分组推荐将近期探针任务以及运算/对称广度任务用于翻译,以用于临床试验。本文描述了这些任务中的每一项符合分组用于推荐进一步开发任务的标准的方式。