• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Restoration by Prostaglandins E(2) and F (2) (alpha) of Resveratrol-Induced Suppression of Hepatoma Cell Invasion in Culture.前列腺素 E（2）和 F（2）（α）恢复白藜芦醇对培养肝癌细胞侵袭的抑制作用。
Cytotechnology. 2003 Nov;43(1-3):155-9. doi: 10.1023/b:cyto.0000039903.22449.79.
2
Resveratrol inhibits hepatoma cell invasion by suppressing gene expression of hepatocyte growth factor via its reactive oxygen species-scavenging property.白藜芦醇通过其清除活性氧的特性抑制肝细胞生长因子的基因表达，从而抑制肝癌细胞的侵袭。
Clin Exp Metastasis. 2004;21(5):445-51. doi: 10.1007/s10585-004-2698-1.
3
Resveratrol suppresses hepatoma cell invasion independently of its anti-proliferative action.白藜芦醇可独立于其抗增殖作用抑制肝癌细胞侵袭。
Cancer Lett. 2001 Jun 26;167(2):151-6. doi: 10.1016/s0304-3835(01)00476-1.
4
Assay systems for screening food components that have anti-proliferative and anti-invasive activity to rat ascites hepatoma cells: In vitro and ex vivo effects of green tea extract.筛选具有抗增殖和抗侵袭活性的食物成分的分析系统：绿茶提取物的体外和体内效应。
Cytotechnology. 1997 Jan;23(1-3):127-32. doi: 10.1023/A:1007951231617.
5
Inhibitory effect of coffee on hepatoma proliferation and invasion in culture and on tumor growth, metastasis and abnormal lipoprotein profiles in hepatoma-bearing rats.咖啡对培养的肝癌细胞增殖和侵袭以及对荷肝癌大鼠肿瘤生长、转移和异常脂蛋白谱的抑制作用。
J Nutr Sci Vitaminol (Tokyo). 2004 Feb;50(1):38-44. doi: 10.3177/jnsv.50.38.
6
Antiproliferative and anti-invasive effect of piceatannol, a polyphenol present in grapes and wine, against hepatoma AH109A cells.葡萄和葡萄酒中含有的一种多酚——白皮杉醇对肝癌AH109A细胞的抗增殖和抗侵袭作用。
J Biomed Biotechnol. 2012;2012:672416. doi: 10.1155/2012/672416. Epub 2012 Feb 8.
7
Anti-proliferative effect of pterostilbene on rat hepatoma cells in culture.对苯二酚对培养大鼠肝癌细胞的抗增殖作用。
Cytotechnology. 2015 Aug;67(4):671-80. doi: 10.1007/s10616-014-9758-4. Epub 2014 Jul 2.
8
Anti-invasive activity of α-tocopherol against hepatoma cells in culture via protein kinase C inhibition.α-生育酚通过抑制蛋白激酶 C 对培养的肝癌细胞的抗侵袭作用。
J Clin Biochem Nutr. 2011 May;48(3):251-7. doi: 10.3164/jcbn.10-117. Epub 2011 Apr 13.
9
Inhibitory effect of gingerol on the proliferation and invasion of hepatoma cells in culture.姜酚对培养肝癌细胞增殖和侵袭的抑制作用。
Cytotechnology. 2008 Jun;57(2):129-36. doi: 10.1007/s10616-008-9121-8. Epub 2008 Jan 23.
10
Inhibitory effect of ascorbic Acid on the proliferation and invasion of hepatoma cells in culture.抗坏血酸对培养的肝癌细胞增殖和侵袭的抑制作用。
Cytotechnology. 2005 Jan;47(1-3):133-8. doi: 10.1007/s10616-005-3750-y.

引用本文的文献

1
The Role of Resveratrol in Liver Disease: A Comprehensive Review from In Vitro to Clinical Trials.白藜芦醇在肝脏疾病中的作用：从体外到临床试验的综合综述。
Nutrients. 2021 Mar 13;13(3):933. doi: 10.3390/nu13030933.
2
Hypoglycemic effect of resveratrol in type 2 diabetic model db/db mice and its actions in cultured L6 myotubes and RIN-5F pancreatic β-cells.白藜芦醇对 2 型糖尿病 db/db 小鼠的降血糖作用及其对培养的 L6 肌管和 RIN-5F 胰岛β细胞的作用。
J Clin Biochem Nutr. 2011 May;48(3):237-44. doi: 10.3164/jcbn.10-119. Epub 2011 Apr 13.
3
Inhibitory effect of gingerol on the proliferation and invasion of hepatoma cells in culture.姜酚对培养肝癌细胞增殖和侵袭的抑制作用。
Cytotechnology. 2008 Jun;57(2):129-36. doi: 10.1007/s10616-008-9121-8. Epub 2008 Jan 23.

本文引用的文献

1
Assay systems for screening food components that have anti-proliferative and anti-invasive activity to rat ascites hepatoma cells: In vitro and ex vivo effects of green tea extract.筛选具有抗增殖和抗侵袭活性的食物成分的分析系统：绿茶提取物的体外和体内效应。
Cytotechnology. 1997 Jan;23(1-3):127-32. doi: 10.1023/A:1007951231617.
2
Hypolipidemic action of dietary resveratrol, a phytoalexin in grapes and red wine, in hepatoma-bearing rats.膳食白藜芦醇（一种存在于葡萄和红酒中的植物抗毒素）对荷肝癌大鼠的降血脂作用。
Life Sci. 2003 Aug 1;73(11):1393-400. doi: 10.1016/s0024-3205(03)00469-7.
3
Potentiation of invasive activity of hepatoma cells by reactive oxygen species is mediated by autocrine/paracrine loop of hepatocyte growth factor.活性氧对肝癌细胞侵袭活性的增强作用是由肝细胞生长因子的自分泌/旁分泌环路介导的。
Biochem Biophys Res Commun. 2003 May 23;305(1):160-5. doi: 10.1016/s0006-291x(03)00725-3.
4
Inhibitory effect of a selective cyclooxygenase-2 inhibitor on liver metastasis of colon cancer.选择性环氧化酶-2抑制剂对结肠癌肝转移的抑制作用
Int J Cancer. 2002 Aug 10;100(5):515-9. doi: 10.1002/ijc.10508.
5
Nonsteroidal anti-inflammatory drugs for treatment of advanced gastric cancer: cyclooxygenase-2 is involved in hepatocyte growth factor mediated tumor development and progression.用于治疗晚期胃癌的非甾体抗炎药：环氧合酶-2参与肝细胞生长因子介导的肿瘤发生和进展。
Med Hypotheses. 2001 Oct;57(4):503-5. doi: 10.1054/mehy.2001.1374.
6
Expression of hepatocyte growth factor/scatter factor, its activator, inhibitors and the c-Met receptor in human cancer cells.肝细胞生长因子/分散因子、其激活剂、抑制剂及c-Met受体在人类癌细胞中的表达
Int J Oncol. 2001 Oct;19(4):857-63.
7
Resveratrol suppresses hepatoma cell invasion independently of its anti-proliferative action.白藜芦醇可独立于其抗增殖作用抑制肝癌细胞侵袭。
Cancer Lett. 2001 Jun 26;167(2):151-6. doi: 10.1016/s0304-3835(01)00476-1.
8
HGF triggers activation of the COX-2 gene in rat gastric epithelial cells: action mediated through the ERK2 signaling pathway.肝细胞生长因子触发大鼠胃上皮细胞中COX-2基因的激活：通过ERK2信号通路介导的作用。
FASEB J. 1999 Dec;13(15):2186-94. doi: 10.1096/fasebj.13.15.2186.
9
Resveratrol prevents apoptosis in K562 cells by inhibiting lipoxygenase and cyclooxygenase activity.白藜芦醇通过抑制脂氧合酶和环氧化酶的活性来防止K562细胞凋亡。
Eur J Biochem. 1999 Oct 1;265(1):27-34. doi: 10.1046/j.1432-1327.1999.00630.x.
10
Comparative study of radical scavenger and antioxidant properties of phenolic compounds from Vitis vinifera cell cultures using in vitro tests.利用体外试验对葡萄细胞培养物中酚类化合物的自由基清除剂和抗氧化性能进行比较研究。
Life Sci. 1997;61(21):2103-10. doi: 10.1016/s0024-3205(97)00883-7.

前列腺素 E（2）和 F（2）（α）恢复白藜芦醇对培养肝癌细胞侵袭的抑制作用。

Restoration by Prostaglandins E(2) and F (2) (alpha) of Resveratrol-Induced Suppression of Hepatoma Cell Invasion in Culture.

机构信息

Department of Applied Biological Science, Tokyo Noko University, Saiwaicho 3-5-8, Fuchu, Tokyo, 183-8509, Japan.

出版信息

Cytotechnology. 2003 Nov;43(1-3):155-9. doi: 10.1023/b:cyto.0000039903.22449.79.

DOI:10.1023/b:cyto.0000039903.22449.79
PMID:19003221
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3449602/
Abstract

In our previous study, resveratrol, a polyphenolic compound in grapes with antioxidative property, and resveratol-loaded rat serum (RS) were found to suppress the invasion of AH109A cells, an ascite hepatoma cell line. The aim of the present study was to investigate whether and which prostaglandins (PGs) would be involved in the invasion of AH109A cells and its suppression by resveratrol and resveratrol-loaded RS, using an in vitro invasion assay system. Not only PGE(2) but also PGF(2) (alpha) stimulated the spontaneous invasion of AH109A cells.They also canceled the resveratrol-induced suppression of hepatoma cell invasion. Results obtained suggest an involvement of PGs, especially PGE(2), in the invasion of hepatoma cells.

摘要

在我们之前的研究中，白藜芦醇，葡萄中的一种具有抗氧化特性的多酚化合物，以及负载白藜芦醇的大鼠血清（RS）被发现能够抑制腹水肝癌细胞系 AH109A 细胞的侵袭。本研究的目的是使用体外侵袭测定系统，探讨白藜芦醇和负载白藜芦醇的 RS 是否以及哪种前列腺素（PG）参与 AH109A 细胞的侵袭及其抑制。不仅 PGE（2），而且 PGF（2）（alpha）刺激 AH109A 细胞的自发侵袭。它们还取消了白藜芦醇诱导的肝癌细胞侵袭抑制。研究结果表明前列腺素，特别是 PGE（2），参与了肝癌细胞的侵袭。